基本信息:
- 专利标题： 글리코실화된 수식된 플라빈 아데닌 디뉴클레오티드 의존성 글루코스 탈수소효소
- 专利标题（英）：KR101850178B1 - A glycosylated modified flavin adenine dinucleotide dependent glucose dehydrogenase
- 申请号：KR1020147030170 申请日：2013-05-03
- 公开(公告)号：KR101850178B1 公开(公告)日：2018-05-31
- 发明人： 뒤펠하르트무트 , 마이어토마스 , 타케미하엘
- 申请人： 에프. 호프만-라 로슈 아게
- 申请人地址： 스위스 체하-**** 바젤 그렌짜체스트라쎄 ***
- 专利权人： 에프. 호프만-라 로슈 아게
- 当前专利权人： 에프. 호프만-라 로슈 아게
- 当前专利权人地址： 스위스 체하-**** 바젤 그렌짜체스트라쎄 ***
- 代理人： 특허법인코리아나
- 优先权： EP121667034 2012-05-03
- 国际申请： PCT/EP2013/059313 2013-05-03
- 国际公布： WO2013164477 2013-11-07
- 主分类号： C12N9/04
- IPC分类号： C12N9/04 ; C12P21/00 ; G01N33/66 ; C12Q1/54
Subject of the invention is a flavin adenine dinucleotide dependent glucose dehydrogenase or its active fragment formulas that are glycosylated, wherein the mature Aspergillus duck material FAD-GDH wild-type sequence SEQ ID No: N2 according to the second (wild-type) .; Being substituted with one or more amino acids at least one asparagine residue selected from the group consisting of N168 and N346 are not suitable for the glycosylation, the potential glycosylation of the seat in this position, respectively, have been activated to remove or fire. Of 2 (wild-type) The formula of Plastic to empty adenine dinucleotide-dependent dehydrogenase or a functional fragment substituted N2S, N168P, N168SP, and N346D derived from: mature Aspergillus duck material FAD-GDH wild-type sequence SEQ ID No It has one or more.
公开/授权文献:
- KR1020150001775A 글리코실화된 수식된 플라빈 아데닌 디뉴클레오티드 의존성 글루코스 탈수소효소 公开/授权日：2015-01-06