基本信息:
- 专利标题: 림프양 조직에 줄기 세포와 조상 세포 결합을 저해하고, 그리고 림프 조직에서 배 중심을 재생하기 위한 조성물과 방법
- 专利标题(英):KR101833204B1 - Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues
- 申请号:KR1020137006660 申请日:2011-08-18
- 公开(公告)号:KR101833204B1 公开(公告)日:2018-03-02
- 发明人: 데이셔테레사
- 申请人: 데이셔 테레사
- 申请人地址: **** Columbia Street, Seattle, WA *****, U.S.A.
- 专利权人: 데이셔 테레사
- 当前专利权人: 데이셔 테레사
- 当前专利权人地址: **** Columbia Street, Seattle, WA *****, U.S.A.
- 代理人: 장훈
- 优先权: US61/374,943 2010-08-18; US61/441,485 2011-02-10; US61/449,372 2011-03-04
- 国际申请: PCT/US2011/048297 2011-08-18
- 国际公布: WO2012024519 2012-02-23
- 主分类号: A61K31/573
- IPC分类号: A61K31/573 ; A61K35/28 ; A61K38/13 ; A61K45/06 ; C07K16/28
摘要:
본발명은림프조직내에존재하는배 중심에줄기세포결합의차단을비롯하여, 장기와조직에줄기세포결합을저해하는조성물과방법에관계한다. 림프조직에서배 중심을재생하기위한조성물과방법이개시된다. 조성물내에어쥬번트, CD40, CD28과 IL-21 수용체에대한효현제, 그리고 CD20에대한길항제가포함된다.
摘要(英):
The invention, including the blocking of stem cells binds to germinal center present in the lymphoid tissues, relates to compositions and methods for inhibiting stem cell coupled to the organs and tissues. The composition and method for reproducing the germinal centers in lymphatic tissues is disclosed. Agonists and antagonists are included for CD20 on the adjuvant, CD40, CD28 and IL-21 receptors in the composition.
公开/授权文献:
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K31/00 | 含有机有效成分的医药配制品 |
--------A61K31/33 | .杂环化合物 |
----------A61K31/573 | ..在21位取代的,例如可的松、地塞米松、强的松 |