基本信息:
- 专利标题: 종양 표적화 광치료제 및 그 제조방법
- 专利标题(英):A tumor-targeted phototherapeutic compond and method for preparing the same
- 专利标题(中):肿瘤靶向光治疗剂及其制备方法
- 申请号:KR1020160045964 申请日:2016-04-15
- 公开(公告)号:KR101750658B1 公开(公告)日:2017-06-27
- 发明人: 김종승 , 신원섭 , 한지유
- 申请人: 고려대학교 산학협력단
- 申请人地址: 서울특별시 성북구 안암로 ***, 고려대학교 (안암동*가)
- 专利权人: 고려대학교 산학협력단
- 当前专利权人: 고려대학교 산학협력단
- 当前专利权人地址: 서울특별시 성북구 안암로 ***, 고려대학교 (안암동*가)
- 代理人: 정은열
- 主分类号: A61K31/437
- IPC分类号: A61K31/437 ; A61K31/436 ; A61K31/4192 ; A61K31/4188 ; A61K41/00
The invention light tumor targeting agents and as it relates to a process for the preparation, more specifically, when activated by a light stimulus, topography is converted into the active form isomerase kinase I inhibitor precursor unit; When activated by a light stimulus, the fluorescence signal emitting unit which provides a fluorescent signal; And to a tumor targeting light treatment, and a manufacturing method including the tumor cells targeted unit for deriving a specific targeting to the cancer cells.
According to the invention, provided with a so exhibit high specificity and easy activation by an external light stimulus, and further capable of tumor targeting light therapeutic agent and a method of manufacturing the monitored in vivo by optical means only to cancer cells compared to normal cells the bar presents a new approach to the development of a wide range of small-molecule cancer chemotherapy can.
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K31/00 | 含有机有效成分的医药配制品 |
--------A61K31/33 | .杂环化合物 |
----------A61K31/335 | ..仅有氧作为环杂原子的,例如制霉色基素 |
------------A61K31/40 | ...有仅以1个氮作为环杂原子的五元环的,例如舒必利、琥珀酰亚胺、托尔米丁、甲氧吡丁苯 |
--------------A61K31/4353 | ....与杂环邻位稠合或迫位稠合的 |
----------------A61K31/437 | .....含有氮作为环杂原子的五元环的杂环系统,例如中氮茚、β咔啉 |