基本信息:
- 专利标题： PDE10 억제제 및 관련 조성물 및 방법
- 专利标题（英）：Pde10 inhibitors and related compositions and methods
- 专利标题（中）：PDE10 PDE10抑制剂及相关组合物和方法
- 申请号：KR1020157000406 申请日：2011-03-10
- 公开(公告)号：KR101713453B1 公开(公告)日：2017-03-07
- 发明人： 컷쉘,네일,에스. , 게이그,제니퍼,린, , 윌러,토마스,네일, , 리틀,토마스,엘.
- 申请人： 오메로스 코포레이션
- 申请人地址： *** Elliott Avenue West, Seattle, Washington *****, U.S.A.
- 专利权人： 오메로스 코포레이션
- 当前专利权人： 오메로스 코포레이션
- 当前专利权人地址： *** Elliott Avenue West, Seattle, Washington *****, U.S.A.
- 代理人： 손민
- 优先权： US61/313,544 2010-03-12; US61/430,841 2011-01-07
- 国际申请： PCT/US2011/027927 2011-03-10
- 国际公布： WO2011112828 2011-09-15
- 主分类号： C07D417/10
- IPC分类号： C07D417/10 ; C07D413/10 ; A61K31/427
Is described are compounds that inhibit PDE10, also various symptoms, e.g., (but not limited to), neurological disorders such as psychotic disorders, anxiety disorders, movement disorders and / or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, language, amnesia, facial palsy, cerebral polio, sleeping disorders, pain, toe turret syndrome, schizophrenia, delusional disorder, bipolar disorder, post traumatic stress disorder, drug induced psychosis, phobia , compulsive disorders, attention disorders, there is provided a compound having utility in the treatment of disruptive behavior disorders, autism, depression, dementia, cognitive disorders, epilepsy, insomnia and multiple sclerosis. In addition, a composition comprising the compound to be combined with a carrier acceptable as a pharmaceutical, as well as a process related to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of this is described.
公开/授权文献:
- KR1020150008515A PDE10 억제제 및 관련 조성물 및 방법 公开/授权日：2015-01-22
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D417/00 | 杂环化合物，含两个或更多个杂环、至少有1个环有氮原子和硫原子作为仅有的杂环原子，C07D415/00组不包含的 |
| --------C07D417/02 | .含有两个杂环 |
| ----------C07D417/10 | ..被含芳环的碳链连接的 |