Sterile sampling system includes a sampler assembly and interface assembly. Each assembly includes a housing, each housing forms a separate sterile container for each assembly. Airlock is placed in the container for disinfection sterilization combination of sampler assembly and interface assembly in use. Resealable fluid connection is arranged in order to operate the airlock. Sampler assembly and the interface assembly, and an outer protective surface comprising a sampler and interface assembly each housing formed when combined with each other, the outer protective surface is sterilized container inside the airlock and the outside of the non-air which is sterile and internal a wall provided with an airtight seal between the sterile air. Resealable fluid connection is in the at least one air lock a through a liquid connecting member and at least one liquid connection members across the sterilizing container and the air lock, in use, from the respective sampler assembly and interface assembly being contained inside the sterilization container is configured to be movable for contact with the other connecting member of the fluid coupling without any contact with the inside surface, the connecting member is configured so that liquid can be continuously re-sealed, block, separated at the time of use.