基本信息:
- 专利标题: 항원에 대한 면역 반응 증강을 위한 글리코실세라마이드의 용도
- 专利标题(英):Use of glycosylceramides for enhancing the immune response to antigens
- 专利标题(中):用于增强对抗原免疫应答的谷氨酰胺
- 申请号:KR1020107014861 申请日:2008-12-05
- 公开(公告)号:KR101566847B1 公开(公告)日:2015-11-06
- 发明人: 세라빈센트
- 申请人: 아비박스
- 申请人地址: *, rue de la Baume, ***** Paris FRANCE
- 专利权人: 아비박스
- 当前专利权人: 아비박스
- 当前专利权人地址: *, rue de la Baume, ***** Paris FRANCE
- 代理人: 유미특허법인
- 优先权: US60/992,460 2007-12-05
- 国际申请: PCT/IB2008/003945 2008-12-05
- 国际公布: WO2009101475 2009-08-20
- 主分类号: A61K31/7032
- IPC分类号: A61K31/7032 ; A61K31/70 ; A61K39/395 ; A61P31/00
摘要:
본발명은식 I의화합물을포함하는조성물을제공한다. 또한, 항원및 상기조성물의투여에의한, 상기항원에대한개체의면역반응을증강시키는방법을제공한다. 상기증강된면역반응은체액성면역반응, CD4+ T 세포반응, CD8+ T 세포반응일수 있거나, 또는항원제시세포의활성화를초래할수 있다. 또한, 식 I의화합물을포함하는조성물과항원의근육내투여에의한면역반응증강방법도제공한다.
摘要(英):
The present invention provides a composition comprising a compound of formula I. In addition, by administration of the antigen and the composition, it provides a method for enhancing the immune response of the object for the antigen. The enhancement of the immune response can result in the activation of the humoral immune response, CD4 + T cell responses, CD8 + T cells may be a reaction, or an antigen presenting cell. In addition, the method for increasing the immune response caused by intramuscular administration of antigen and composition comprising the compound of formula I is also provided.
公开/授权文献:
- KR1020100094556A 항원에 대한 면역 반응 증강을 위한 글리코실세라마이드의 용도 公开/授权日:2010-08-26
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K31/00 | 含有机有效成分的医药配制品 |
--------A61K31/70 | .碳水化合物;糖;其衍生物 |
----------A61K31/7028 | ..含有通过配糖键与非糖化合物连接的糖基的化合物 |
------------A61K31/7032 | ...与多元醇连接,即含有两个或3个游离或者酯化的羟基的化合物,例如葡萄糖基—二酰基甘油酯、乳糖酸、神经节苷脂 |