基本信息:
- 专利标题： 메탈로프로테이즈 ＡＤＡＭ１７에 의한 도파민성 신경세포로의 분화 조절 조성물
- 专利标题（英）：Composition of Regulating Differentiation into Dopaminergic Neurons by ADAM17
- 专利标题（中）：通过ADAM17调节分化为多巴胺能神经元的组成
- 申请号：KR1020120017667 申请日：2012-02-21
- 公开(公告)号：KR101485163B1 公开(公告)日：2015-01-23
- 发明人： 백자현 , 윤세현
- 申请人： 고려대학교 산학협력단
- 申请人地址： 서울특별시 성북구 안암로 ***, 고려대학교 (안암동*가)
- 专利权人： 고려대학교 산학협력단
- 当前专利权人： 고려대학교 산학협력단
- 当前专利权人地址： 서울특별시 성북구 안암로 ***, 고려대학교 (안암동*가)
- 代理人： 이처영
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K31/7105 ; A61K31/7088 ; A61P25/00
The present invention relates to neural stem cells or neural method for controlling the differentiation to increase the activity, or further comprising the step of suppressing, neural stem cells or neural progenitor cells, dopaminergic neurons of the ADAM17 of progenitor cells and brain neurological disease therapeutic composition that, induced by the death of dopaminergic neurons, such as Parkinson's disease and by methods and compositions according to the present invention modulate the activity of, ADAM17 against neural stem cells or neural progenitor cells, to dopaminergic neurons increases in the midbrain region can achieve a therapeutic effect of diseases and may also be by inhibiting the activity, increase the therapeutic efficacy, such as tumor diseases.
公开/授权文献:
- KR1020130096112A 메탈로프로테이즈 ＡＤＡＭ１７에 의한 도파민성 신경세포로의 분화 조절 조성물 公开/授权日：2013-08-29
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K48/00 | 含有插入到活体细胞中的遗传物质以治疗遗传病的医药配制品；基因治疗 |