基本信息:
- 专利标题： 오메가 트랜스아미나아제의 조기질 순환을 이용한 광학 활성 아미노산의 제조방법
- 专利标题（英）：Method for production enantiopure amino acids using ω-transaminase with cosubstrate recycling
- 专利标题（中）：使用ω-转氨酶与同位素回收生产对映体纯氨基酸的方法
- 申请号：KR1020120074035 申请日：2012-07-06
- 公开(公告)号：KR101479718B1 公开(公告)日：2015-01-08
- 发明人： 신종식 , 박을수
- 申请人： 연세대학교 산학협력단
- 申请人地址： 서울특별시 서대문구 연세로 ** (신촌동, 연세대학교)
- 专利权人： 연세대학교 산학협력단
- 当前专利权人： 연세대학교 산학협력단
- 当前专利权人地址： 서울특별시 서대문구 연세로 ** (신촌동, 연세대학교)
- 代理人： 특허법인충현
- 主分类号： C12P13/06
- IPC分类号： C12P13/06 ; C12P13/08 ; C12N9/10 ; C12N9/78
The present invention trans relates to a method for producing an optically active amino acid using an early quality circulation of transaminase, of chain amino acid transport and reaction of Kane switch acid of the amino acid by the enzyme, omega transaminase amine of the amine substrate by was coupled by reaction in the amino acid early quality transitioning to and characterized in that cyclic reaction, the present invention can produce various optically active amino acid of high purity with high efficiency to fix the lower reaction equilibrium constant problem in the prior transaminase various It can be industrially used in the production process of an amino acid. In addition, by the present invention has a high reactivity and stability can easily produce a variety of unnatural amino acids that are used as pharmaceutical precursor can be used in the pharmaceutical, food additives, various kinds of animal feed manufacture.
公开/授权文献:
- KR1020140006619A 오메가 트랜스아미나아제의 조기질 순환을 이용한 광학 활성 아미노산의 제조방법 公开/授权日：2014-01-16
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C12 | 生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程 |
| ----C12P | 发酵或使用酶的方法合成目标化合物或组合物或从外消旋混合物中分离旋光异构体 |
| ------C12P13/00 | 含氮有机化合物的制备 |
| --------C12P13/04 | .α-氨基酸或β-氨基酸 |
| ----------C12P13/06 | ..丙氨酸；亮氨酸；异亮氨酸；丝氨酸；高丝氨酸 |