基本信息:
- 专利标题： 신규한 지속형 인간 성장호르몬의 정제 방법
- 专利标题（英）：A novel method for purifying long-acting human growth hormone
- 专利标题（中）：一种用于纯化长效人生长激素的新方法
- 申请号：KR1020120060641 申请日：2012-06-05
- 公开(公告)号：KR101460266B1 公开(公告)日：2014-11-11
- 发明人： 안지원 , 강길부 , 전창봉 , 이동억 , 김기완 , 이정민 , 이윤정 , 박순재 , 정혜신 , 이상미
- 申请人： 씨제이헬스케어 주식회사 , (주)알테오젠
- 申请人地址： 서울특별시 중구 동호로 *** (쌍림동,씨제이제일제당빌딩)
- 专利权人： 씨제이헬스케어 주식회사,(주)알테오젠
- 当前专利权人： 씨제이헬스케어 주식회사,(주)알테오젠
- 当前专利权人地址： 서울특별시 중구 동호로 *** (쌍림동,씨제이제일제당빌딩)
- 代理人： 손민
- 主分类号： C07K14/61
- IPC分类号： C07K14/61 ; C07K19/00 ; C07K1/16 ; A61K38/27
The present invention relates to highly pure purification of the persisted NexP-hGH human growth hormone, in particular (a) containing the human growth hormone and alpha-1-antitrypsin in NexP-hGH variants are fused long-acting human growth hormone applying a biological fluid to an anion exchange resin chromatography; (B) applying the resulting eluate in a biological fluid, or step (a) comprising the hGH-NexP the hydrophobic resin chromatography; And (c) filled with the long-acting human growth biological fluid, step (a), or step (b) the resin and the resulting eluate was attached to anti-alpha-1-antitrypsin antibody fragment comprising the hormone in NexP-hGH comprising applying to an affinity chromatography, to a purification method of the persisted NexP-hGH human growth hormone.
公开/授权文献:
- KR1020130136883A 신규한 지속형 인간 성장호르몬의 정제 방법 公开/授权日：2013-12-13
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07K | 肽 |
| ------C07K14/00 | 具有多于20个氨基酸的肽；促胃液素；生长激素释放抑制因子；促黑激素；其衍生物 |
| --------C07K14/415 | .来自植物 |
| ----------C07K14/44 | ..来自原生动物门 |
| ------------C07K14/61 | ...生长激素（GH）（促生长素） |