基本信息:
- 专利标题: 보툴리눔 독소의 국소 적용 및 경피 전달을 위한 조성물 및 방법
- 专利标题(英):Compositions and methods for topical application and transdermal delivery of botulinum toxins
- 专利标题(中):用于局部应用和经皮递送肉毒杆菌毒素的组合物和方法
- 申请号:KR1020147005118 申请日:2006-03-03
- 公开(公告)号:KR101453963B1 公开(公告)日:2014-10-22
- 发明人: 데이크마이클디. , 워제이콥엠.
- 申请人: 레반스 테라퓨틱스, 아이엔씨.
- 申请人地址: **** Gateway Blvd, Newark, CA *****, U.S.A.
- 专利权人: 레반스 테라퓨틱스, 아이엔씨.
- 当前专利权人: 레반스 테라퓨틱스, 아이엔씨.
- 当前专利权人地址: **** Gateway Blvd, Newark, CA *****, U.S.A.
- 代理人: 리앤목특허법인
- 优先权: US60/658,434 2005-03-03
- 国际申请: PCT/US2006/007830 2006-03-03
- 国际公布: WO2006094263 2006-09-08
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; A61K47/38 ; A61K39/08 ; A61P17/00
The present invention relates to a formulation (formulation) for improving the transdermal delivery of the botulinum toxin. The agent may, for example, oily minutes group (branching group) or a group effect (efficiency group) and a positive charge to the charged backbone having a non-comprises a botulinum toxin coupled by a covalent bond. The agent may also first fraction (partitioning agent), oligo- may include a bridge (oligo-bridge), and polyvalent anions include a bridge (bridge polyanion), optionally a viscosity modifier. It can be used for the treatment of related problems, wherein the formulation is designed for topical application onto the skin of the patient's wrinkles, hyperhidrosis, and other health. Kits for administration are also disclosed.
公开/授权文献:
- KR1020140032510A 보툴리눔 독소의 국소 적용 및 경피 전달을 위한 조성물 및 방법 公开/授权日:2014-03-14
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K47/00 | 以所用的非有效成分为特征的医用配制品,如载体、惰性添加剂 |
--------A61K47/48 | .非有效成分被化学键键合到有效成分上,例如聚合物药物轭合物 |