基本信息:
- 专利标题: 방사성 핵종이 표지되고 약물이 담지된 고분자 하이드로겔 및 이의 제조방법, 및 이를 유효성분으로 함유하는 암 치료용 약학 조성물
- 专利标题(英):Radioisotope-labeled and drug-loaded polymeric hydrogel and method for preparing the same, and pharmaceutical composition comprising the same for treating cancer
- 专利标题(中):放射性同位素标记和负载药物的聚合物水凝胶及其制备方法,以及包含其的用于治疗癌症的药物组合物
- 申请号:KR1020110096205 申请日:2011-09-23
- 公开(公告)号:KR101351515B1 公开(公告)日:2014-01-15
- 发明人: 이창문 , 정환정 , 임석태 , 손명희
- 申请人: 전북대학교산학협력단
- 申请人地址: 전라북도 전주시 덕진구 백제대로 *** (덕진동*가)
- 专利权人: 전북대학교산학협력단
- 当前专利权人: 전북대학교산학협력단
- 当前专利权人地址: 전라북도 전주시 덕진구 백제대로 *** (덕진동*가)
- 代理人: 김순웅
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; A61K51/12 ; A61K51/02 ; A61K9/06
This invention relates to radionuclide labeling and the drug-impregnated polymer hydrogel and preparation method thereof, and a pharmaceutical composition for treating cancer containing the same as an active ingredient. Polymer hydrogel according to the invention cover a radionuclide to the biodegradable polymer directly and has excellent labeling efficiency and labeling stability of radionuclide by loading the drug during the hydrogel formation can be minimized glass radionuclides, topically lesions by injection directly to the site to stay stably in the lesion emitting radiation it can be effectively used in the treatment of incurable diseases such as cancer. Thus, the polymer hydrogel according to the present invention can be in the treatment effect by the radionuclide, as well as the therapeutic effect can be expected by the drug at the same time to increase the therapeutic effects of the lesions.
公开/授权文献:
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K47/00 | 以所用的非有效成分为特征的医用配制品,如载体、惰性添加剂 |
--------A61K47/48 | .非有效成分被化学键键合到有效成分上,例如聚合物药物轭合物 |