基本信息:
- 专利标题： 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브
- 专利标题（英）：RNAi Probes Targeting Cancer-Related Proteins
- 专利标题（中）：靶向癌症相关蛋白的RNAi探针
- 申请号：KR1020117025408 申请日：2003-08-21
- 公开(公告)号：KR101238701B1 公开(公告)日：2013-03-05
- 发明人： 얀센브르크하르트 , 글리브마틴이. , 시냐프스키막심 , 베랄디엘리아나 , 트루가코스이오안니스피. , 고노스에프스타치오스에스.
- 申请人： 더 유니버시티 오브 브리티쉬 콜롬비아
- 申请人地址： University Industry Liaison Office, #***-**** Agronomy Road, Vancouver, British Columbia V*T *Z*, Canada
- 专利权人： 더 유니버시티 오브 브리티쉬 콜롬비아
- 当前专利权人： 더 유니버시티 오브 브리티쉬 콜롬비아
- 当前专利权人地址： University Industry Liaison Office, #***-**** Agronomy Road, Vancouver, British Columbia V*T *Z*, Canada
- 代理人： 리앤목특허법인
- 优先权： US60/405,193 2002-08-21; US60/408,152 2002-09-03; US60/472,387 2003-05-20
- 国际申请： PCT/CA2003/001277 2003-08-21
- 国际公布： WO2004018676 2004-03-04
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/712
The invention includes a variety of prostate cancer, sarcomas, such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, degenerative large cell lymphoma, and melanoma cancers; And provides an RNAi sequence that is useful in the treatment of Alzheimer's disease. The sequence is a cluster Stephen Lin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5, targeting the MITF and B-raf. The invention also various cancers, including prostate cancer, sarcomas, such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, degenerative large cell lymphoma, and melanoma; And provides for the use of the RNAi sequences for the treatment of Alzheimer's disease, and provides a method for treating said disease comprising administering the RNA molecule having RNAi activity to the object, including a human.
公开/授权文献:
- KR1020110122883A 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브 公开/授权日：2011-11-11