基本信息:
- 专利标题： ＮＡＤＨ 선택적 형광 화학센서
- 专利标题（英）：NADH-Selective Fluorescence Chemosensor
- 专利标题（中）：NADH选择性荧光化学传感器
- 申请号：KR1020090015942 申请日：2009-02-25
- 公开(公告)号：KR101083031B1 公开(公告)日：2011-11-16
- 发明人： 한민수 , 장석규 , 안지연 , 장현혜 , 이수정 , 김미희 , 이나희 , 류대훈 , 최길돈 , 정대영
- 申请人： 중앙대학교 산학협력단 , 서울대학교산학협력단
- 申请人地址： 서울 동작구 흑석동 ***
- 专利权人： 중앙대학교 산학협력단,서울대학교산학협력단
- 当前专利权人： 중앙대학교 산학협력단,서울대학교산학협력단
- 当前专利权人地址： 서울 동작구 흑석동 ***
- 代理人： 특허법인다나
- 主分类号： G01N33/573
- IPC分类号： G01N33/573 ; G01N33/533
NADH, 형광 화학센서
The present invention relates to a fluorescent chemical sensor capable of selectively detecting the NADH. The compounds of formula (I) is detected in the NADH it has a high selectivity against the other anions. Fluorescence changes due to coupling with the compound and NADH in the formula (1) with the naked eye can also be observed, and a rapid detection can be immediately after the reaction and, because it can be detected in a variety of pH ranges, by using a composition comprising a compound of formula (I) the NADH in a biological sample and normal sample can be efficiently detected. And also the activity of various enzymes by the composition using the NADH or NAD as a coenzyme can be measured, it is possible to high-speed screen for activators or inhibitors of the enzyme. NADH, fluorescent chemical sensor
公开/授权文献:
- KR1020100096868A ＮＡＤＨ 선택적 형광 화학센서 公开/授权日：2010-09-02
信息查询:
EspacenetIPC结构图谱:
| G | 物理 |
| --G01 | 测量；测试 |
| ----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
| ------G01N33/00 | 利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料 |
| --------G01N33/48 | .生物物质，例如血、尿（G01N33/02至G01N33/14，G01N33/26，G01N33/44，G01N33/46优先；种子发芽能力测定入A01C1/02）；血球计数器 |
| ----------G01N33/483 | ..生物物质的物理分析 |
| ------------G01N33/53 | ...免疫测定法；生物特有的结合方法的测定；相应的生物物质 |
| --------------G01N33/573 | ....用于酶或同功酶 |