基本信息:
- 专利标题： 非天然型アミノ酸の製造方法およびその中間体
- 专利标题（英）：Preparation and intermediates of the non-natural amino acids
- 申请号：JP2006512531 申请日：2005-04-18
- 公开(公告)号：JPWO2005102991A1 公开(公告)日：2008-03-13
- 发明人： 石井 裕 , 裕 石井 , 藤本 亮輔 , 亮輔 藤本
- 申请人： ダイソー株式会社
- 专利权人： ダイソー株式会社
- 当前专利权人： ダイソー株式会社
- 优先权： JP2004122808 2004-04-19
- 主分类号： C07C269/06
- IPC分类号： C07C269/06 ; C07B53/00 ; C07C271/22 ; C07D213/61 ; C07D213/73
Formula (A1), the following formula (A2) and a compound represented by the following formula (A3) [Formula 1]
Are reacted, a compound represented by the following formula (B) [Formula 2]
To produce, then, to deprotection of the protecting group of carboxyl group, non-natural amino acid represented by the following formula (C), characterized in that to decarboxylation Formula 3]
Through the process for producing (above
formulas, X 1,
X 2 denotes a leaving group,
R 1 is an aromatic group, unsaturated heterocyclic group or means an
R 6 CO group,
R 2 and
R 3, means a protected carboxyl group, R
4 means a protected amino group, R
5 is a hydrogen atom, an aliphatic hydrocarbon group, an aromatic group or a heterocyclic group,, R
6 is refers to an aromatic group or an unsaturated heterocyclic group,, p, q and r are 0.).
公开/授权文献:
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07C | 无环或碳环化合物 |
| ------C07C269/00 | 氨基甲酸的衍生物，即含有如下任何基团的化合物NCOO，NCOHal，NCOO，NCOHal或NCHalHal，氮原子不属于硝基或亚硝基的制备 |
| --------C07C269/06 | .由不涉及形成氨基甲酸酯基的反应 |