基本信息:
- 专利标题： ベンジル化合物
- 专利标题（英）：Benzyl compounds
- 申请号：JP2016574023 申请日：2016-08-25
- 公开(公告)号：JP6116782B1 公开(公告)日：2017-04-19
- 发明人： 矢野 真也 , 若杉 裕樹 , 岩永 陽介
- 申请人： 積水メディカル株式会社
- 申请人地址： 東京都中央区日本橋二丁目1番3号
- 专利权人： 積水メディカル株式会社
- 当前专利权人： 積水メディカル株式会社
- 当前专利权人地址： 東京都中央区日本橋二丁目1番3号
- 代理人： 特許業務法人アルガ特許事務所; 高野 登志雄; 中嶋 俊夫; 村田 正樹; 山本 博人
- 优先权： JP2015168711 2015-08-28 JP2015227234 2015-11-20 JP2016124192 2016-06-23
- 国际申请： JP2016074888 JP 2016-08-25
- 主分类号： C07K1/06
- IPC分类号： C07K1/06 ; C07B51/00
By improving the solubility in an organic solvent of a compound to protect the functional groups, the separation after the reaction, the purification provides an easy if occupied protecting group without solidifying or insolubilizing.
The general formula (1)
(Wherein, X
1 is -CH
2 OR
14 (wherein R
14 represents a hydrogen atom, halogenoalkyl group or an active ester-type protecting group), - CH
2 NHR
15 (wherein, R
15 is a hydrogen atom, a carbon number 1-6 straight or branched chain alkyl group, or an aralkyl group), a halogenomethyl group, methyl azide group, a formyl group, or an
oxime; R 1, R 2, R 3, R 4 and at least one formula of R
5 (2)
In indicates a group represented by the remaining is a hydrogen atom, a halogen atom, an alkyl group or an alkoxy group having 1 to 4 carbon atoms having 1 to 4 carbon atoms; R
6 is a straight-chain or branched-chain having 1 to 16 carbon atoms represents an alkylene group; X
2 is O or CONR
16 (wherein R
16 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms) shows a; a is the formula (3), (4), (5) , (6), (7), (8), (9), (10), (11), (12) or (13) a group represented by)
In represented by benzyl compounds.
公开/授权文献:
- JPWO2017038650A1 ベンジル化合物 公开/授权日：2017-08-31