基本信息:
- 专利标题: Method of screening substance in microwell array
- 专利标题(中):在MICROWELL阵列中筛选物质的方法
- 申请号:JP2008124416 申请日:2008-05-12
- 公开(公告)号:JP2008292478A 公开(公告)日:2008-12-04
- 发明人: HUNTER IAN W , BRENAN COLIN J H , KANIGAN TANYA S
-
申请人:
Massachusetts Inst Of Technol
, マサチューセッツ インスティテュート オブ テクノロジーMassachusetts Institute Of Technology -
专利权人:
Massachusetts Inst Of Technol
,マサチューセッツ インスティテュート オブ テクノロジーMassachusetts Institute Of Technology -
当前专利权人:
Massachusetts Inst Of Technol
,マサチューセッツ インスティテュート オブ テクノロジーMassachusetts Institute Of Technology - 优先权: US85012301 2001-05-07
- 主分类号: G01N35/02
- IPC分类号: G01N35/02 ; G01N35/10 ; B01F13/00 ; B01J4/02 ; B01J19/00 ; B01L3/00 ; B01L3/02 ; B01L99/00 ; B81B1/00 ; B81C99/00 ; C12M1/00 ; C40B60/14 ; C40B70/00 ; G01N30/46 ; G01N30/60 ; G01N30/82 ; G01N35/00 ; G01N37/00
摘要:
PROBLEM TO BE SOLVED: To provide a method of reacting a large number of reagents or analytes in the micro-liter order or in further smaller amounts, and then realizing the analysis. SOLUTION: This method is for manufacturing and using an apparatus for manipulating and analyzing materials, including cells, in a liquid or a liquid suspension as a large number of microscopic samples. Parallel through-holes are formed in a platen and loaded with a liquid. Loading may be performed in such a way as to create a gradient, with respect to the position of the through-holes, of the concentration of a particular substance or of another quantity. Mixing of the contents of the through-holes may be obtained by bringing the filled microwell arrays into contact with each other with registration of the individual through-holes. COPYRIGHT: (C)2009,JPO&INPIT
摘要(中):
要解决的问题:提供一种使微量试剂或分析物以微升或更少的量反应的方法,然后实现分析。 解决方案:该方法用于制造和使用用于操作和分析液体或液体悬浮液中的材料(包括电池)的装置作为大量微观样品。 平行的通孔形成在压板中并装载液体。 可以以相对于通孔的位置产生特定物质的浓度或另一数量的浓度的梯度来进行装载。 可以通过使填充的微孔阵列通过各个通孔对准而彼此接触来获得通孔内容物的混合。 版权所有(C)2009,JPO&INPIT