发明专利
JP2004300156A New quinoline, tetrahydroquinazoline and pyrimidine derivative and method of treatment related to use thereof
审中-公开
基本信息:
- 专利标题： New quinoline, tetrahydroquinazoline and pyrimidine derivative and method of treatment related to use thereof
- 申请号：JP2004107965 申请日：2004-03-31
- 公开(公告)号：JP2004300156A 公开(公告)日：2004-10-28
- 发明人： SEKIGUCHI YOSHIISA , SHIKANUMA KOSUKE , OMODERA KATSUNORI , BUSUJIMA TAKESHI , TRAN THUY-ANH , HAN SANGDON , CASPER MARTIN , KRAMER BRYAN A , SEMPLE GRAEME , ZOU NING
- 申请人： Arena Pharmaceuticals Inc , Taisho Pharmaceut Co Ltd , アリーナ ファーマシューチカルズ インコーポレーテッド , 大正製薬株式会社
- 专利权人： Arena Pharmaceuticals Inc,Taisho Pharmaceut Co Ltd,アリーナ ファーマシューチカルズ インコーポレーテッド,大正製薬株式会社
- 当前专利权人： Arena Pharmaceuticals Inc,Taisho Pharmaceut Co Ltd,アリーナ ファーマシューチカルズ インコーポレーテッド,大正製薬株式会社
- 优先权： US45853003 2003-03-31; US49591103 2003-08-19; US51018603 2003-10-09; US53036003 2003-12-16
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; A61K31/4706 ; A61K31/4709 ; A61K31/498 ; A61K31/505 ; A61K31/506 ; A61K31/513 ; A61K31/517 ; A61P1/14 ; A61P3/04 ; A61P3/06 ; A61P3/10 ; A61P9/00 ; A61P9/10 ; A61P9/12 ; A61P25/00 ; A61P25/08 ; A61P25/14 ; A61P25/16 ; A61P25/18 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P25/30 ; A61P43/00 ; C07D215/42 ; C07D239/48 ; C07D239/94 ; C07D239/95 ; C07D401/12 ; C07D403/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D417/14
摘要：
PROBLEM TO BE SOLVED: To provide a new quinoline, tetrahydroquinazoline, and pyrimidine derivative and method of treatment related to the use thereof. SOLUTION: The present invention relates to new compounds of formula (I), which act as MCH receptor antagonists. The compositions are useful in pharmaceutical compositions whose use includes prophylaxis or treatment of improving memory function, sleeping and arousal, anxiety, depression, mood disorders, seizure, obesity, diabetes, appetite and eating disorders, cardiovascular disease, hypertension, dyslipidemia, myocardial infarction, binge eating disorders including bulimia, anorexia, mental disorders including manic depression, schizophrenia, delirium, dementia, stress, cognitive disorders, attention deficit disorder, substance abuse disorders and dyskinesias including Parkinson's disease, epilepsy, and addiction. COPYRIGHT: (C)2005,JPO&NCIPI
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/33 | .杂环化合物 |
| ----------A61K31/335 | ..仅有氧作为环杂原子的，例如制霉色基素 |
| ------------A61K31/40 | ...有仅以1个氮作为环杂原子的五元环的，例如舒必利、琥珀酰亚胺、托尔米丁、甲氧吡丁苯 |
| --------------A61K31/47 | ....喹啉；异喹啉 |