基本信息:
- 专利标题: Method for producing a glycoprotein with a human-type sugar chain
- 申请号:JP2000586923 申请日:1999-12-08
- 公开(公告)号:JP2002543760A 公开(公告)日:2002-12-24
- 发明人: 敏臣 吉田 , 和仁 藤山 , 達治 関
- 申请人: 和仁 藤山 , 達治 関
- 专利权人: 和仁 藤山,達治 関
- 当前专利权人: 和仁 藤山,達治 関
- 优先权: JP35058498 1998-12-09
- 主分类号: A01H5/00
- IPC分类号: A01H5/00 ; C07K14/415 ; C12N5/10 ; C12N9/08 ; C12N9/10 ; C12N15/09 ; C12N15/82 ; C12P21/00 ; C12P21/02
(57) [summary] The present invention provides a useful glycoprotein having a human-type sugar chain. The invention relates to a method for producing a glycoprotein having a human-type sugar chain, into plant cells, by introducing a gene of a gene and a heterologous glycoprotein glycosyltransferases, obtaining a transformed plant cell, and obtained comprising the step of culturing a transformed plant cells. The glycosyltransferase is capable of performing a transfer reaction of a galactose residue to a non-reducing terminal acetylglucosamine residues. Glycoprotein with the human-type sugar chain comprises a core sugar chain and an outer sugar chain, this core sugar chain comprises a plurality of mannose and acetylglucosamine, and this outer sugar chain, the terminal sugar with a non-reducing terminal galactose It comprises a chain portion, with a straight chain structure or a branched structure. Glycoprotein having the human-type sugar chains, because it contains no fucose or xylose, show no antigenicity against humans.
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A01 | 农业;林业;畜牧业;狩猎;诱捕;捕鱼 |
----A01H | 新植物或获得新植物的方法;通过组织培养技术的植物再生 |
------A01H5/00 | 有花植物,即被子植物 |