基本信息:
- 专利标题： ANTIHYPERTENSIVE PEPTIDE DERIVED FROM MEAT PROTEIN
- 申请号：JP2000048143 申请日：2000-02-24
- 公开(公告)号：JP2001233898A 公开(公告)日：2001-08-28
- 发明人： ARIHARA KEIZO , NAKAJIMA YASUYOSHI , ITO MAKOTO , AKIMOTO MASANOBU , SAMEJIMA TAKASHI , MOTONO KAZUO
- 申请人： PRIMA MEAT PACKERS LTD
- 专利权人： PRIMA MEAT PACKERS LTD
- 当前专利权人： PRIMA MEAT PACKERS LTD
- 优先权： JP2000048143 2000-02-24
- 主分类号： A23L1/305
- IPC分类号： A23L1/305 ; A23L33/10 ; A23L33/17 ; A23L33/18 ; A61K35/34 ; A61K38/00 ; A61K38/17 ; A61P9/12 ; A61P43/00 ; C07K5/083 ; C07K5/093 ; C07K5/097 ; C07K7/06 ; C12N9/99 ; C12P21/02
摘要：
PROBLEM TO BE SOLVED: To provide new peptides having antihypertensive action or angiotensin I-converting enzyme-inhibiting activity obtained from meat ranked as important food, and to provide a pharmacological composition comprising at least one of the peptides as an active component. SOLUTION: A peptide composition comprising pentapeptides having respective structures of Met-Asn-Pro-Pro-Lys and Ile-Thr-Thr-Asn-Pro is obtained by hydrolyzing meat protein or myosin of a principal meat protein by the action of a protease such thermolysin or protease K. These two pentapeptides and respective tripeptides having partial amino acid sequences Met-Asn-Pro and Pro-Pro-Lys of one of the pentapeptides have both of angiotensin I-converting enzyme-inhibiting activity and antihypertensive action. These peptides are highly safe and can be applied to food for prophylaxis of hypertension and amelioration of its symptom.
公开/授权文献:
- JP3651878B2 Blood pressure lowering peptides derived from meat protein 公开/授权日：2005-05-25
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A23 | 其他类不包含的食品或食料；及其处理 |
| ----A23L | 不包含在A21D或A23B至A23J小类中的食品、食料或非酒精饮料；它们的制备或处理，如烹调、营养品质的改进、物理处理（不能为本小类完全包含的成型或加工入A23P）；食品或食料的一般保存 |
| ------A23L1/00 | 食品或食料；它们的制备或处理 |
| --------A23L1/29 | .改变食品的营养性质；营养制品 |
| ----------A23L1/30 | ..含添加剂的 |
| ------------A23L1/305 | ...氨基酸类、肽或蛋白质类 |