基本信息:
- 专利标题： Tricyclic sulfones as ror gamma modulators
- 申请号：IL26647419 申请日：2019-05-06
- 公开(公告)号：IL266474D0 公开(公告)日：2019-07-31
- 发明人： DHAR T G MURALI , XIAO HAI-YUN , MARCOUX DAVID , BATT DOUGLAS G , BEAUDOIN BERTRAND MYRA , YANG MICHAEL G , XIAO ZILI , ZHU YEHENG , WEIGELT CAROLYN A
- 申请人： SQUIBB BRISTOL MYERS CO , DHAR T G MURALI , XIAO HAI YUN , MARCOUX DAVID , BATT DOUGLAS G , BEAUDOIN BERTRAND MYRA , YANG MICHAEL G , XIAO ZILI , ZHU YEHENG , WEIGELT CAROLYN A
- 专利权人： SQUIBB BRISTOL MYERS CO,DHAR T G MURALI,XIAO HAI YUN,MARCOUX DAVID,BATT DOUGLAS G,BEAUDOIN BERTRAND MYRA,YANG MICHAEL G,XIAO ZILI,ZHU YEHENG,WEIGELT CAROLYN A
- 当前专利权人： SQUIBB BRISTOL MYERS CO,DHAR T G MURALI,XIAO HAI YUN,MARCOUX DAVID,BATT DOUGLAS G,BEAUDOIN BERTRAND MYRA,YANG MICHAEL G,XIAO ZILI,ZHU YEHENG,WEIGELT CAROLYN A
- 优先权： US201662419607 2016-11-09
- 主分类号： C07D
- IPC分类号： C07D20060101
摘要：
or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.