发明公开
EP4378940A1 POLYCYCLIC COMPOUND FOR INHIBITING RNA HELICASE DHX33, AND APPLICATION OF COMPOUND
审中-实审
基本信息:
- 专利标题： POLYCYCLIC COMPOUND FOR INHIBITING RNA HELICASE DHX33, AND APPLICATION OF COMPOUND
- 申请号：EP22832064.4 申请日：2022-06-28
- 公开(公告)号：EP4378940A1 公开(公告)日：2024-06-05
- 发明人： ZHANG, Yandong , LI, Xianglu
- 申请人： Shenzhen Keye Life Technologies, Co., Ltd.
- 申请人地址： CN Shenzhen, Guangdong 518122 Room 501, R & D Building Salubris Pharmaceutical Industry Park 8 Juliu Road, Pingshan District
- 专利权人： Shenzhen Keye Life Technologies, Co., Ltd.
- 当前专利权人： Shenzhen Keye Life Technologies, Co., Ltd.
- 当前专利权人地址： CN Shenzhen, Guangdong 518122 Room 501, R & D Building Salubris Pharmaceutical Industry Park 8 Juliu Road, Pingshan District
- 代理机构： Cabinet Laurent & Charras
- 优先权： CN 202110724794 2021.06.29
- 国际申请： CN2022102010 2022.06.28
- 国际公布： WO2023274251 2023.01.05
- 主分类号： C07D409/14
- IPC分类号： C07D409/14 ; C07D417/14 ; C07D403/14 ; C07D413/14 ; C07D405/14 ; C07D403/12 ; C07D401/14 ; C07D471/04 ; A61P35/00 ; A61P29/00 ; A61P31/14 ; A61K31/4184 ; A61K31/427 ; A61K31/437 ; A61K31/506 ; A61K31/422 ; A61K31/4439
摘要：
The present invention relates to a polycyclic compound for inhibiting RNA helicase DHX33, and an application of the compound. In particular, the present invention relates to a compound as represented by formula I or a pharmaceutically acceptable form thereof, a pharmaceutical composition comprising the same, a preparation method therefor, and a medical use thereof for preventing and/or treating DHX33-associated diseases.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D409/00 | 杂环化合物，含两个或更多个杂环，至少有1个环有硫原子作为仅有的杂环原子 |
| --------C07D409/14 | .含3个或更多个杂环 |