基本信息:
- 专利标题： FORMULATIONS FOR SMALL INTESTINAL DELIVERY
- 申请号：EP24158414.3 申请日：2015-02-20
- 公开(公告)号：EP4353255A3 公开(公告)日：2024-07-03
- 发明人： TUCKER, Sean , TRAGER, George
- 申请人： Vaxart, Inc.
- 申请人地址： US South San Francisco, CA 94080 170 Harbor Way, Suite 300
- 专利权人： Vaxart, Inc.
- 当前专利权人： Vaxart, Inc.
- 当前专利权人地址： US South San Francisco, CA 94080 170 Harbor Way, Suite 300
- 代理机构： J A Kemp LLP
- 优先权： US 1461942386P 2014.02.20
- 分案原申请号： 15752216.0 2015.02.20
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K31/7088 ; A61K31/713 ; A61K9/28 ; A61P37/04
摘要：
Provided herein are compositions and methods for generating an immunogenic response in humans. Such compositions include an immunogenic biological agent encompassed by (ii) an agent that directs delivery of the immunogenic biological agent to the ileum of the human, wherein agent (ii) is an enteric coating (e.g., Eudragit®) that has a threshold pH 5.8-6.8. Further provided are methods for designing such compositions, e.g., for vaccines.
公开/授权文献:
- EP4353255A2 FORMULATIONS FOR SMALL INTESTINAL DELIVERY 公开/授权日：2024-04-17
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |