A controller (180) may identify a plurality of sets of potential parameters associated with operation of an engine (160), wherein each set of potential parameters includes a potential setting of a turbine (210) of a variable geometry turbocharger (VGT) (220) of the engine (160) and a potential setting of an intake throttle valve (ITV) (204) of the engine. The controller (180) may determine, based on the plurality of sets of potential parameters, a plurality of sets of predicted values, wherein each set of predicted values includes a predicted outlet pressure of a compressor (202) of the VGT (220) and a predicted temperature of an exhaust gas of the engine (160). The controller (180) may determine respective scores of the plurality of sets of predicted values, and may select, based on the respective scores, a particular set of predicted values of the plurality of sets of predicted values. The controller (180) may thereby control the turbine (210) of the VGT (220) and the ITV (204).