基本信息:
- 专利标题： MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF
- 申请号：EP23194905.8 申请日：2017-01-06
- 公开(公告)号：EP4306525A2 公开(公告)日：2024-01-17
- 发明人： DEBIEN, Laurent, Pierre Paul , JAEN, Juan, Carlos , KALISIAK, Jaroslaw , LAWSON, Kenneth V. , LELETI, Manmohan Reddy , LINDSEY, Erick, Allen , MILES, Dillon Harding , NEWCOMB, Eric , POWERS, Jay Patrick , ROSEN, Brandon Reid , SHARIF, Ehesan UI
- 申请人： Arcus Biosciences, Inc.
- 申请人地址： US Hayward, CA 94545 3928 Point Eden Way
- 代理机构： Müller, Christian Stefan Gerd
- 优先权： US201662324077 P 20160418
- 主分类号： C07D487/04
- IPC分类号： C07D487/04
摘要：
Compounds that modulate the conversion of AMP to adenosine by 5'- nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5'-nucleotidase, ecto is also provided.
公开/授权文献:
- EP4306525A3 MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF 公开/授权日：2024-03-20
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D487/00 | 在稠环系中含有氮原子作为仅有的杂环原子的杂环化合物，不包含在C07D451/00至C07D477/00组中 |
| --------C07D487/02 | .在稠合系中含有两个杂环 |
| ----------C07D487/04 | ..邻位稠合系 |