基本信息:
- 专利标题： PHOTOREDOX RADICAL BENZYLATION PROCESS
- 申请号：EP21305263.2 申请日：2021-03-05
- 公开(公告)号：EP4053096A1 公开(公告)日：2022-09-07
- 发明人： DAVIOUD-CHARVET, Elisabeth , DONZEL, Maxime , ELHABIRI, Mourad
- 申请人： Centre national de la recherche scientifique , Université de Strasbourg , Université de Haute Alsace
- 申请人地址： FR 75016 Paris 3, rue Michel Ange; FR 67000 Strasbourg 4, rue Blaise Pascal; FR 68093 Mulhouse Cedex 2 Rue des Frères Lumière
- 代理机构： Lavoix
- 主分类号： C07C46/02
- IPC分类号： C07C46/02 ; C07C50/14
摘要：
The present invention relates to a method for the preparation of a compound having the formula (I):
wherein:
• R 1 , R 2 , R 3 , and R 4 are in particular H or halogen,
• R 5 is in particular (C 1 -C 6 )alkyl,
• R 6 is a group of formula -CH=CH 2 or a group having the below formula (II):
said method comprising a reacting step carried out under light irradiation in the presence of an iron catalyst, a heteroatomic base, and a HAT agent.
wherein:
• R 1 , R 2 , R 3 , and R 4 are in particular H or halogen,
• R 5 is in particular (C 1 -C 6 )alkyl,
• R 6 is a group of formula -CH=CH 2 or a group having the below formula (II):
said method comprising a reacting step carried out under light irradiation in the presence of an iron catalyst, a heteroatomic base, and a HAT agent.