基本信息:
- 专利标题： HETEROCYCLIC COMPOUND AND APPLICATION THEREOF
- 申请号：EP19826282.6 申请日：2019-06-27
- 公开(公告)号：EP3816154A1 公开(公告)日：2021-05-05
- 发明人： FUJIMOTO, Tatsuhiko , FUKUDA, Koichiro , SUGIMOTO, Hiromichi , RIKIMARU, Kentaro , BANNO, Yoshihiro , MATSUMOTO, Takahiro , TOKUNAGA, Norihito , TOMATA, Yoshihide , ISHICHI, Yuji , MARUI, Shogo , ODA, Tsuneo , MIYAZAKI, Tohru , HOASHI, Yasutaka , HATTORI, Yasushi , KAJITA, Yuichi , MIYANOHANA, Yuhei , KOIKE, Tatsuki
- 申请人： Takeda Pharmaceutical Company Limited
- 申请人地址： JP Osaka-shi, Osaka 541-0045 1-1, Doshomachi 4-chome Chuo-ku
- 代理机构： Jones, Nicholas Andrew
- 优先权： JP2018125332 20180629
- 国际公布： WO2020004536 20200102
- 主分类号： C07D211/56
- IPC分类号： C07D211/56 ; A61K31/445 ; A61K31/506 ; A61P25/00 ; A61P25/20 ; A61P43/00 ; C07D401/14 ; C07D405/14
摘要：
The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity.
A compound represented by the formula (I):
wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.
A compound represented by the formula (I):
wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D211/00 | 杂环化合物，含氢化吡啶环，不与其他环稠合 |
| --------C07D211/04 | .只有氢或碳原子直接连在环氮原子上 |
| ----------C07D211/06 | ..环原子间或环原子与非环原子间无双键 |
| ------------C07D211/08 | ...有烃基或取代的烃基直接连在环碳原子上 |
| --------------C07D211/56 | ....氮原子 |