发明公开
EP3564674A1 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE
有权
基本信息:
- 专利标题： HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE
- 申请号：EP19178774.6 申请日：2007-11-01
- 公开(公告)号：EP3564674A1 公开(公告)日：2019-11-06
- 发明人： KOSMEDER, Jerry , LEFEVER, Mark , JOHNSON, Donald , FARRELL, Michael , ZHILINA, Zhanna , BIENIARZ, Christopher
- 申请人： Ventana Medical Systems, Inc.
- 申请人地址： 1910 E. Innovation Park Drive Tucson, Arizona 85755 US
- 专利权人： Ventana Medical Systems, Inc.
- 当前专利权人： Ventana Medical Systems, Inc.
- 当前专利权人地址： 1910 E. Innovation Park Drive Tucson, Arizona 85755 US
- 代理机构： Bond, Christopher William
- 优先权： US856133P 20061101
- 主分类号： G01N33/532
- IPC分类号： G01N33/532 ; G01N33/533 ; G01N33/58 ; C12Q1/68 ; C07D271/12 ; C07D495/04
摘要：
A method for performing a multiplexed diagnostic assay, such as for two or more different targets in a sample, is described. One embodiment comprised contacting the sample with two or more specific binding moieties that bind specifically to two or more different targets. The two or more specific binding moieties are conjugated to different haptens, and at least one of the haptens is an oxazole, a pyrazole, a thiazole, a nitroaryl compound other than dinitrophenyl, a benzofurazan, a triterpene, a urea, a thiourea, a rotenoid, a coumarin, a cyclolignan, a heterobiaryl, an azo aryl, or a benzodiazepine. The sample is contacted with two or more different anti-hapten antibodies that can be detected separately. The two or more different anti-hapten antibodies may be conjugated to different detectable labels.
公开/授权文献:
IPC结构图谱:
| G | 物理 |
| --G01 | 测量；测试 |
| ----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
| ------G01N33/00 | 利用不包括在G01N1/00至G01N31/00组中的特殊方法来研究或分析材料 |
| --------G01N33/48 | .生物物质，例如血、尿（G01N33/02至G01N33/14，G01N33/26，G01N33/44，G01N33/46优先；种子发芽能力测定入A01C1/02）；血球计数器 |
| ----------G01N33/483 | ..生物物质的物理分析 |
| ------------G01N33/53 | ...免疫测定法；生物特有的结合方法的测定；相应的生物物质 |
| --------------G01N33/531 | ....免疫化学试验物质的制备 |
| ----------------G01N33/532 | .....示踪免疫化学物品的制备 |