发明公开
EP3368660A1 METHODS OF GENERATING T-CELLS FROM STEM CELLS AND IMMUNOTHERAPEUTIC METHODS USING THE T-CELLS
审中-实审
基本信息:
- 专利标题： METHODS OF GENERATING T-CELLS FROM STEM CELLS AND IMMUNOTHERAPEUTIC METHODS USING THE T-CELLS
- 申请号：EP16860902.2 申请日：2016-10-28
- 公开(公告)号：EP3368660A1 公开(公告)日：2018-09-05
- 发明人： CROOKS, Gay, M. , MONTEL-HAGEN, Amelie , SEET, Christopher, S.
- 申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 申请人地址： 1111 Franklin Street, 12th Floor Oakland, CA 94607-5200 US
- 专利权人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 当前专利权人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 当前专利权人地址： 1111 Franklin Street, 12th Floor Oakland, CA 94607-5200 US
- 代理机构： J A Kemp
- 优先权： US201562248931P 20151030; US201562265204P 20151209; US201662359456P 20160707
- 国际公布： WO2017075389 20170504
- 主分类号： C12N5/0783
- IPC分类号： C12N5/0783 ; C12N5/00 ; A61K35/17 ; C07K14/725 ; C07K16/00
摘要：
Methods and composition for production of T cells are provided. Also provided are therapeutic methods using engineered T cells. For example, in certain aspects methods include preparing three dimensional cell culture compositions comprising stroma cells and hematopoietic stem or progenitor cells in a serum-free medium for producing T cells.