发明公开
EP3356393A1 COMPOSITIONS AND METHODS FOR ADJOINING TYPE I AND TYPE II EXTRACELLULAR DOMAINS AS HETEROLOGOUS CHIMERIC PROTEINS
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基本信息:
- 专利标题： COMPOSITIONS AND METHODS FOR ADJOINING TYPE I AND TYPE II EXTRACELLULAR DOMAINS AS HETEROLOGOUS CHIMERIC PROTEINS
- 申请号：EP16852655.6 申请日：2016-09-30
- 公开(公告)号：EP3356393A1 公开(公告)日：2018-08-08
- 发明人： SCHREIBER, Taylor , FROMM, George , DE SILVA, Suresh , SCHILLING, Neal
- 申请人： Heat Biologics, Inc.
- 申请人地址： 801 Capitola Drive Bay 12 Durham, NC 27713 US
- 专利权人： Heat Biologics, Inc.
- 当前专利权人： KOPFKINO IP, LLC
- 当前专利权人地址： KOPFKINO IP, LLC
- 代理机构： Grund, Martin
- 优先权： US201562235727P 20151001; US201562263313P 20151204; US201662372574P 20160809
- 国际公布： WO2017059168 20170406
- 主分类号： C07K14/525
- IPC分类号： C07K14/525 ; C07K14/705 ; C12N7/00 ; C12N15/85 ; A61K38/17 ; A61K38/19
摘要：
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07K | 肽 |
| ------C07K14/00 | 具有多于20个氨基酸的肽；促胃液素；生长激素释放抑制因子；促黑激素；其衍生物 |
| --------C07K14/415 | .来自植物 |
| ----------C07K14/44 | ..来自原生动物门 |
| ------------C07K14/525 | ...肿瘤坏死因子（TNF） |