基本信息:
- 专利标题： SYSTEM AND METHOD FOR IMPROVED TRANSIENT PROTEIN EXPRESSION IN CHO CELLS
- 申请号：EP16741788.0 申请日：2016-07-13
- 公开(公告)号：EP3322813A1 公开(公告)日：2018-05-23
- 发明人： ZMUDA, Jonathan , LIU, Chao Yan
- 申请人： Life Technologies Corporation
- 申请人地址： Legal Department IP Docketing 5823 Newton Drive Carlsbad, California 92008 US
- 专利权人： Life Technologies Corporation
- 当前专利权人： Life Technologies Corporation
- 当前专利权人地址： Legal Department IP Docketing 5823 Newton Drive Carlsbad, California 92008 US
- 代理机构： HGF Limited
- 优先权： US201562191969P 20150713
- 国际公布： WO2017011598 20170119
- 主分类号： C12P21/02
- IPC分类号： C12P21/02 ; C12N5/00
摘要：
The present invention is directed generally to systems and methods suitable for high level expression of recombinant proteins in suspension CHO cells. In particular, the invention allows introduction of the invention obviates the need to replace, replenish or supplement the growth medium during the procedure. The invention also relates to compositions and kits useful for culturing and transforming/transfecting suspension CHO cells.
IPC结构图谱:
| C | 化学；冶金 |
| --C12 | 生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程 |
| ----C12P | 发酵或使用酶的方法合成目标化合物或组合物或从外消旋混合物中分离旋光异构体 |
| ------C12P21/00 | 肽或蛋白质的制备 |
| --------C12P21/02 | .有两个或更多个氨基酸的已知序列，如谷胱苷肽 |