发明公开
EP3256197A1 SIMULTANEOUS ESTIMATION OF RESPIRATORY PARAMETERS BY REGIONAL FITTING OF RESPIRATORY PARAMETERS
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基本信息:
- 专利标题： SIMULTANEOUS ESTIMATION OF RESPIRATORY PARAMETERS BY REGIONAL FITTING OF RESPIRATORY PARAMETERS
- 专利标题（中）：呼吸参数的区域拟合同时评估呼吸参数
- 申请号：EP16702201.1 申请日：2016-01-12
- 公开(公告)号：EP3256197A1 公开(公告)日：2017-12-20
- 发明人： ALBANESE, Antonio , VICARIO, Francesco , WANG, Dong , KARAMOLEGKOS, Nikolaos , CHBAT, Nicolas Wadih
- 申请人： Koninklijke Philips N.V.
- 申请人地址： High Tech Campus 5 5656 AE Eindhoven NL
- 专利权人： Koninklijke Philips N.V.
- 当前专利权人： KONINKLIJKE PHILIPS N.V.
- 当前专利权人地址： KONINKLIJKE PHILIPS N.V.
- 代理机构： Müller, Frank
- 优先权： US201562115182P 20150212
- 国际公布： WO2016128846 20160818
- 主分类号： A61M16/00
- IPC分类号： A61M16/00 ; A61B5/085 ; A61B5/087
摘要：
A medical ventilator (10) performs a method including: receiving measurements of pressure of air inspired by or expired from a ventilated patient (12) operatively connected with the medical ventilator; receiving measurements of air flow into or out of the ventilated patient operatively connected with the medical ventilator; dividing a breath time interval into a plurality of fitting regions (60); and simultaneously estimating respiratory system's resistance and compliance or elastance, and respiratory muscle pressure in each fitting region by fitting to a time series of pressure and air flow samples in that fitting region. In one approach, the fitting includes parameterizing the respiratory muscle pressure by a continuous differentiable function, such as a polynomial function, over the fitting region. In another approach, the fitting is to an equation of motion of the lungs in each fitting region, while monotonicity constraints and inequalities bounding at least the respiratory muscle pressure Pmus(t) and respiratory system's resistence R and compliance C are applied to the respiratory muscle pressure in each region.