发明公开
EP3110790A1 METHODS AND SYSTEMS FOR PURIFYING AN ACETONITRILE WASTE STREAM AND METHODS FOR SYNTHESIZING OLIGONUCLEOTIDES USING PURIFIED ACETONITRILE WASTE STREAMS
有权
基本信息:
- 专利标题： METHODS AND SYSTEMS FOR PURIFYING AN ACETONITRILE WASTE STREAM AND METHODS FOR SYNTHESIZING OLIGONUCLEOTIDES USING PURIFIED ACETONITRILE WASTE STREAMS
- 专利标题（中）：用于清洁ACETONITRILABFALLSTRÖMEN和方法合成寡核苷酸用的方法和系统CLEANEDACETONITRILABFALLSTRÖMEN
- 申请号：EP15751403.5 申请日：2015-02-12
- 公开(公告)号：EP3110790A1 公开(公告)日：2017-01-04
- 发明人： GAJDA, Gregory J. , RILEY, Mark G. , MOHAN, Venkatraman , LORENZ, Sandra M. , COHEN, Alan P.
- 申请人： Honeywell International Inc.
- 申请人地址： Intellectual Property-Patent Services 115 Tabor Road M/S 4D3 P.O.Box 377 Morris Plains, NJ 07950 US
- 专利权人： Honeywell International Inc.
- 当前专利权人： Honeywell International Inc.
- 当前专利权人地址： Intellectual Property-Patent Services 115 Tabor Road M/S 4D3 P.O.Box 377 Morris Plains, NJ 07950 US
- 代理机构： Crooks, Elizabeth Caroline
- 优先权： US201461943701P 20140224; US201462063281P 20141013; US201514608911 20150129
- 国际公布： WO2015126713 20150827
- 主分类号： C07C253/34
- IPC分类号： C07C253/34 ; C07C255/02 ; C07C255/01
摘要：
Methods and systems for purifying an acetonitrile waste stream and methods for synthesizing an oligonucleotide using a purified acetonitrile waste stream are provided. An exemplary method for purifying an acetonitrile waste stream includes providing an acetonitrile waste stream and fractionating the acetonitrile waste stream to produce a single overhead fraction. The method includes condensing the single overhead fraction to produce a condensed single overhead fraction and contacting the condensed single overhead fraction with an adsorbent to produce an acetonitrile stream that comprises an amount of at least one impurity that is reduced relative to the acetonitrile waste stream.
摘要（中）：
提供了用于乙腈和用于使用纯化的乙腈废物流寡核苷酸的合成方法的净化废物流的方法和系统。 用于纯化废物流的乙腈的示例性方法包括提供乙腈废物流和分馏乙腈废物流，以产生一个单一的塔顶馏分。 该方法包括冷凝所述单塔顶馏分以产生冷凝单塔顶馏分并在吸附剂接触的冷凝单塔顶馏分的乙腈流，以产生并包含至少一种杂质的量也相对于乙腈废物流减小。
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07C | 无环或碳环化合物 |
| ------C07C253/00 | 羧酸腈的制备 |
| --------C07C253/32 | .分离；纯化；稳定化；添加剂的使用 |
| ----------C07C253/34 | ..分离；纯化 |