EP3027733B1 3-HYDROXYPROPIONIC ACID PRODUCTION BY RECOMBINANT YEASTS EXPRESSING AN INSECT ASPARTATE 1-DECARBOXYLASE
有权
基本信息:
- 专利标题： 3-HYDROXYPROPIONIC ACID PRODUCTION BY RECOMBINANT YEASTS EXPRESSING AN INSECT ASPARTATE 1-DECARBOXYLASE
- 申请号：EP14752713.9 申请日：2014-07-31
- 公开(公告)号：EP3027733B1 公开(公告)日：2018-09-12
- 发明人： BARNHART, Michelle , NEGRETE-RAYMOND, Ana , FRIAS, Janice , BARBIER, Gui , CATLETT, Michael
- 申请人： Novozymes A/S
- 申请人地址： Krogshoejvej 36 2880 Bagsvaerd DK
- 专利权人： Novozymes A/S
- 当前专利权人： Novozymes A/S
- 当前专利权人地址： Krogshoejvej 36 2880 Bagsvaerd DK
- 代理机构： NZ EPO Representatives
- 优先权： US201361860550P 20130731; US201461976139P 20140407
- 国际公布： WO2015017721 20150205
- 主分类号： C12N1/16
- IPC分类号： C12N1/16 ; C12N9/88 ; C12P7/40 ; C12P7/42
摘要：
Provided herein are recombinant yeast cells having an active 3-Hydroxypropionic Acid (3-HP) pathway and further comprising a heterologous polynucleotide encoding an aspartate 1-decarboxylase (ADC) of the Class Insecta, Bivalvia, Branchioporia, Gastropoda, or Leptocardii. Also described are methods of using the recombinant yeast cells to produce 3-HP and acrylic acid.