![NEW PEPTIDE AND APPLICATION THEREOF](/ep/2016/04/13/EP3006564A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: NEW PEPTIDE AND APPLICATION THEREOF
- 专利标题(中):邻近的DAVON安东尼
- 申请号:EP14801460.8 申请日:2014-05-23
- 公开(公告)号:EP3006564A1 公开(公告)日:2016-04-13
- 发明人: TOYOSHIMA, Hideo , OKAZAKI, Yasushi , YOKOO, Tomotaka , SUGAHARA, Izumi
- 申请人: Saitama Medical University
- 申请人地址: 38, Morohongo Moroyama-machi Iruma-gun, Saitama 350-0495 JP
- 专利权人: Saitama Medical University
- 当前专利权人: Saitama Medical University
- 当前专利权人地址: 38, Morohongo Moroyama-machi Iruma-gun, Saitama 350-0495 JP
- 代理机构: Cabinet Plasseraud
- 优先权: JP2013109801 20130524
- 国际公布: WO2014189127 20141127
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; A61K48/00 ; A61P3/10 ; C07K14/47 ; C12N1/00 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/071 ; C12N5/10
摘要:
Provided are a new peptide, a vector inserting a DNA that codes said peptide, a transformant obtained by transformation with that vector, and applications of said peptide, vector and transformant. The peptide according to the present invention comprises an amino acid sequence set forth in SEQ ID NO: 1, or an amino acid sequence obtained by substituting, deleting or adding one or more amino acids to/from the amino acid sequence set forth in SEQ ID NO: 1. This peptide and the vector inserting a DNA that codes this peptide are suitable for use in an agent for promoting the proliferation of pancreatic hormone-producing cells, or a differentiation induction promoter that induces differentiation to pancreatic hormone-producing cells.
摘要(中):
提供了新的肽,插入编码所述肽的DNA的载体,通过用该载体转化获得的转化体,以及所述肽,载体和转化体的应用。 根据本发明的肽包含SEQ ID NO:1所示的氨基酸序列或通过将SEQ ID NO:1所示的氨基酸序列替换,缺失或添加一个或多个氨基酸而获得的氨基酸序列 NO:1.该肽和载体编码该肽的载体适合用于促进胰腺激素产生细胞增殖的药剂,或诱导分泌胰腺激素产生细胞的分化诱导启动子。
公开/授权文献:
- EP3006564B1 NEW PEPTIDE AND APPLICATION THEREOF 公开/授权日:2019-10-02