
基本信息:
- 专利标题: NANOPARTICLE PEPTIDE COMPOSITIONS
- 专利标题(中):纳米肽组合物
- 申请号:EP14705555.2 申请日:2014-02-06
- 公开(公告)号:EP2964262A1 公开(公告)日:2016-01-13
- 发明人: RADEMACHER, Thomas , WILLIAMS, Phillip
- 申请人: Midatech Ltd.
- 申请人地址: 4 & 5 Dunmore Court, Wootton Road Abingdon, Oxford Oxfordshire 0X13 6BH GB
- 专利权人: Midatech Ltd.
- 当前专利权人: Midatech Ltd.
- 当前专利权人地址: 4 & 5 Dunmore Court, Wootton Road Abingdon, Oxford Oxfordshire 0X13 6BH GB
- 代理机构: Casley, Christopher Stuart
- 优先权: GB201303787 20130304
- 国际公布: WO2014135840 20140912
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; A61P3/08
摘要:
The present invention relates to amylin peptide-carrying nanoparticles, particularly for use in medicine, and includes methods for treatment of disorders, e.g., of blood glucose regulation. Nanoparticle composition comprise a nanoparticle comprising a core comprising a metal and/or a semiconductor; and a corona comprising a plurality of ligands covalently linked to the core, wherein said ligands comprise glutathione; and at least one amylin peptide that is non-covalently bound to the corona.
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K47/00 | 以所用的非有效成分为特征的医用配制品,如载体、惰性添加剂 |
--------A61K47/48 | .非有效成分被化学键键合到有效成分上,例如聚合物药物轭合物 |