基本信息:
- 专利标题： CYCLOPROPANAMINE COMPOUND AND USE THEREOF
- 专利标题（中）：环丙烷AMIN连接及其用途
- 申请号：EP13845823 申请日：2013-10-11
- 公开(公告)号：EP2907802A4 公开(公告)日：2016-04-20
- 发明人： TOMITA NAOKI , TOMITA DAISUKE , TOMINARI YUSUKE , IMAMURA SHINICHI , MORIMOTO SHINJI , KOJIMA TAKUTO , TOYOFUKU MASASHI , HATTORI YASUSHI , KAKU TOMOHIRO , ITO MITSUHIRO
- 申请人： TAKEDA PHARMACEUTICAL
- 专利权人： TAKEDA PHARMACEUTICAL
- 当前专利权人： TAKEDA PHARMACEUTICAL
- 优先权： JP2012227243 2012-10-12; JP2013022534 2013-02-07
- 主分类号： C07C237/40
- IPC分类号： C07C237/40 ; A61K31/166 ; A61K31/167 ; A61K31/415 ; A61K31/4453 ; A61P25/14 ; A61P25/16 ; A61P25/28 ; A61P43/00 ; C07C237/30 ; C07C237/38 ; C07D231/40 ; C07D295/18 ; C12N9/99 ; C12N15/09
摘要：
The present invention provides a compound having a lysine specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, Alzheimer's disease, Parkinson's disease or Huntington's disease, and the like. The present invention relates to a compound represented by the formula wherein A is a hydrocarbon group optionally having substituent(s), or a heterocyclic group optionally having substituent(s); B is a benzene ring optionally having further substituent(s); R 1 , R 2 and R 3 are each independently a hydrogen atom, a hydrocarbon group optionally having substituent(s), or a heterocyclic group optionally having substituent(s); A and R 1 are optionally bonded to each other to form, together with the adjacent nitrogen atom, a cyclic group optionally having substituent(s); and R 2 and R 3 are optionally bonded to each other to form, together with the adjacent nitrogen atom, a cyclic group optionally having substituent(s), or a salt thereof.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07C | 无环或碳环化合物 |
| ------C07C237/00 | 羧酸酰胺，酸部分的碳架进一步被氨基取代 |
| --------C07C237/02 | .羧酰胺基的碳原子连接在碳架的非环碳原子上 |
| ----------C07C237/40 | ..羧酰胺基的氮原子连接在六元芳环碳原子上 |