基本信息:
- 专利标题： METHODS OF TREATING RETROVIRAL INFECTIONS IN FELINES
- 专利标题（中）：法复古CATS治疗病毒感染
- 申请号：EP12799750.0 申请日：2012-06-15
- 公开(公告)号：EP2721147A1 公开(公告)日：2014-04-23
- 发明人： TRAUGER, Richard
- 申请人： CytoDyn, Inc.
- 申请人地址： 1111 Main St. Ste 660 Vancouver, WA 98660-2970 US
- 专利权人： CytoDyn, Inc.
- 当前专利权人： CytoDyn, Inc.
- 当前专利权人地址： 1111 Main St. Ste 660 Vancouver, WA 98660-2970 US
- 代理机构： Dee, Ian Mark
- 优先权： US201161498029P 20110617
- 国际公布： WO2012174392 20121220
- 主分类号： C12N5/16
- IPC分类号： C12N5/16
摘要：
Provided are methods for treating or reducing the likelihood of developing a retroviral infection in a feline, decreasing retroviral virion entry into a feline cell, decreasing retroviral virion budding from a feline cell, or decreasing syncytium transmission in a feline. These methods require the administration of at least one agent that specifically binds to CD11a and/or CD18, or ICAM-1, and/or decreases or prevents the binding of LFA-1 (CD11a/CD18 heterodimer) to ICAM-1. Also provided are veterinary compositions and methods of identifying candidate agents useful for treating or reducing retroviral infection in a feline, decreasing retroviral virion entry into a feline cell, decreasing retroviral virion budding from a feline cell, or decreasing syncytium transmission in a feline.
公开/授权文献:
- EP2721147B1 METHODS OF TREATING RETROVIRAL INFECTIONS IN FELINES 公开/授权日：2018-04-25