基本信息:
- 专利标题： MODULATION OF IMMUNE RESPONSES BY THE POXVIRAL K4 PROTEIN
- 专利标题（中）：免疫反应BY THE K4蛋白天花病毒的调控
- 申请号：EP11779589.8 申请日：2011-11-07
- 公开(公告)号：EP2635687A2 公开(公告)日：2013-09-11
- 发明人： HAUSMANN, Jürgen , HOCHREIN, Hubertus , MEISINGER-HENSCHEL, Christine
- 申请人： Bavarian Nordic A/S
- 申请人地址： Hejreskovvej 10A 3490 Kvistgaard DK
- 专利权人： Bavarian Nordic A/S
- 当前专利权人： Bavarian Nordic A/S
- 当前专利权人地址： Hejreskovvej 10A 3490 Kvistgaard DK
- 代理机构： Bendiksen, Henrik
- 优先权： US410427P 20101105
- 国际公布： WO2012059243 20120510
- 主分类号： C12N15/863
- IPC分类号： C12N15/863 ; C07K14/07 ; C12N15/113
摘要：
The present invention relates to compositions, methods, and uses involving the modulation of K4 protein activity, especially in the treatment of various diseases and in the enhancement of vaccination regimens. The invention relates to poxviruses having reduced or increased K4 protein activity, as well as methods of making and using these poxviruses. The invention further relates to K4 proteins and inhibitors of K4 protein activity, as well as methods for making and using them.
公开/授权文献:
- EP2635687B1 MODULATION OF IMMUNE RESPONSES BY THE POXVIRAL K4 PROTEIN 公开/授权日：2016-12-21