基本信息:
- 专利标题： ISOLATING A TARGET ANALYTE FROM A BODY FLUID
- 申请号：EP11772606.7 申请日：2011-04-20
- 公开(公告)号：EP2561360B9 公开(公告)日：2018-04-11
- 发明人： CLARIZIA, Lisa-Jo, Ann , ADAMS, Eddie, W. , DRYGA, Sergey, A.
- 申请人： DNAE Group Holdings Limited
- 申请人地址： Ugli Campus, Block C, Centre House 56 Wood Lane London W12 7SB GB
- 专利权人： DNAE Group Holdings Limited
- 当前专利权人： DNAE GROUP HOLDINGS LIMITED
- 当前专利权人地址： DNAE GROUP HOLDINGS LIMITED
- 代理机构： Kirkham, Nicholas Andrew
- 优先权： US326588P 20100421; US850203 20100804
- 国际公布： WO2011133630 20111027
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/53 ; G01N33/553
摘要：
The invention generally relates to using magnetic particles and alternating magnet fields to separate a target analyte from a sample. In certain embodiments, methods of the invention involve contacting a sample with magnetic particles including first moieties specific for a target analyte, thereby forming target/particle complexes in the sample, flowing the sample through a channel including second moieties attached to at least one surface of the channel, applying alternating magnetic fields to the flowing sample to result in target/particle complexes being brought into proximity of the surface to bind the second moieties and unbound particles remaining free in the sample, binding the target/particle complexes to the second moieties, and washing away unbound particles and unbound analytes of the sample.
公开/授权文献:
- EP2561360B1 ISOLATING A TARGET ANALYTE FROM A BODY FLUID 公开/授权日：2017-11-08