基本信息:
- 专利标题： PROCÉDÉ DE PRÉPARATION D'UN RADIOTRACEUR
- 专利标题（英）：Method for producing a radioactive tracer
- 专利标题（中）：方法生产放射性示踪剂
- 申请号：EP11713069.0 申请日：2011-03-07
- 公开(公告)号：EP2544993A1 公开(公告)日：2013-01-16
- 发明人： PEROLLIER, Céline , NARAGHI, Kaynoush , BAYOUDH, Sami
- 申请人： Polyintell
- 申请人地址： Polyintell Pharma Parc II Voie de l'Innovation Chaussée du Vexin Centre 303 27100 Val-de-reuil FR
- 专利权人： Polyintell
- 当前专利权人： Polyintell
- 当前专利权人地址： Polyintell Pharma Parc II Voie de l'Innovation Chaussée du Vexin Centre 303 27100 Val-de-reuil FR
- 代理机构： Nony
- 优先权： FR1051707 20100309
- 国际公布： WO2011110994 20110915
- 主分类号： C01B9/08
- IPC分类号： C01B9/08 ; C07B59/00 ; C07D207/12
摘要：
The present invention relates to a method for preparing a radioactive tracer provided with a radioactive fluorine isotope, including at least the following steps consisting in: i) providing a precursor of the radioactive tracer, comprising at least one leaving group completely or partially formed by a labelling entity, wherein said leaving group can be moved by a fluoride ion; ii) providing a molecularly imprinted polymer dedicated to the molecular recognition of at least the aforementioned labelling entity; iii) exposing the precursor to a radioactive fluoride ion source under conditions suitable for the movement of the leaving group by a radioactive fluoride ion; iv) placing the mixture resulting from step (iii) in contact with the molecularly imprinted polymer under conditions suitable for the recognition of the labelling entity; and v) obtaining a solution containing the radioactive tracer provided with a radioactive isotope of fluorine obtained at the end of step (iii).
IPC结构图谱:
| C | 化学；冶金 |
| --C01 | 无机化学 |
| ----C01B | 非金属元素；其化合物 |
| ------C01B9/00 | 制备卤化物的一般方法 |
| --------C01B9/08 | .氟化物 |