发明公开
EP2444408A3 METHOD OF PURIFYING/CONCENTRATING SUGAR CHAIN WITH SUGAR CHAIN-TRAPPING MOLECULE AND METHOD OF ANALYZING SUGAR CHAIN STRUCTURE
审中-公开
基本信息:
- 专利标题： METHOD OF PURIFYING/CONCENTRATING SUGAR CHAIN WITH SUGAR CHAIN-TRAPPING MOLECULE AND METHOD OF ANALYZING SUGAR CHAIN STRUCTURE
- 专利标题（中）：对于糖链ZUCKERKETTENEINFANGENDEM分子清洁/浓度和分析过程方法的糖链结构
- 申请号：EP11192486.6 申请日：2003-12-25
- 公开(公告)号：EP2444408A3 公开(公告)日：2014-01-01
- 发明人： Nishimura, Shinichrio , Niikura, Kenichi , Nakagawa, Hiroaki , Okayama, Minenobu
- 申请人： Shionogi & Co., Ltd.
- 申请人地址： 1-8, Doshomachi 3-chome Chuo-ku Osaka-shi, Osaka 5410045 JP
- 专利权人： Shionogi & Co., Ltd.
- 当前专利权人： Shionogi & Co., Ltd.
- 当前专利权人地址： 1-8, Doshomachi 3-chome Chuo-ku Osaka-shi, Osaka 5410045 JP
- 代理机构： UEXKÜLL & STOLBERG
- 优先权： JP2002378733 20021226
- 主分类号： C07H1/08
- IPC分类号： C07H1/08
摘要：
The present invention provides substance which can specifically interact with sugar chains. Further, the present invention provides a method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of: a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated.
摘要（中）：
本发明提供了可以与糖链特异性地发生相互作用的物质。 此外，本发明提供了用于分离，浓缩或纯化的糖链或样品中的含糖链物质的方法，包括以下步骤的方法：a）使捕捉糖链的载体包含可以与特异性地发生相互作用的物质 糖链与条件下的流体相的样品做了捕捉糖链的载体可以与糖链或含糖链物质反应; b）分离捕捉糖链的载体的从流体相的复合体与糖链或含糖链物质; 和c）暴露该复合的条件并在捕捉糖链的载体与糖链或含糖链物质之间的相互作用至少部分被消除。