基本信息:
- 专利标题： APPARATUS AND METHODS FOR PERFORMING ELECTROCHEMICAL REACTIONS
- 专利标题（中）：装置和方法，以确保电化学反应
- 申请号：EP10780935.2 申请日：2010-05-27
- 公开(公告)号：EP2436075A1 公开(公告)日：2012-04-04
- 发明人： NOBILE, John , ROTH, George, Thomas , REARICK, Todd , SCHULTZ, Jonathan , ROTHBERG, Jonathan, M. , MARRAN, David
- 申请人： Life Technologies Corporation
- 申请人地址： 5791 Van Allen Way Carlsbad, CA 92008 US
- 专利权人： Life Technologies Corporation
- 当前专利权人： LIFE TECHNOLOGIES CORPORATION
- 当前专利权人地址： LIFE TECHNOLOGIES CORPORATION
- 代理机构： Wöhler, Christian
- 优先权： US475311 20090529; US306924P 20100222; US474897 20090529; US785716 20100524
- 国际公布： WO2010138188 20101202
- 主分类号： H01M8/04
- IPC分类号： H01M8/04 ; H01M8/10
摘要：
The invention is directed to apparatus and methods for delivering multiple reagents to, and monitoring, a plurality of analytical reactions carried out on a large-scale array of electronic sensors under minimal noise conditions. In one aspect, the invention provides method of improving signal-to-noise ratios of output signals from the electronic sensors sensing analytes or reaction byproducts by subtracting an average of output signals measured from neighboring sensors where analyte or reaction byproducts are absent. In other aspects, the invention provides an array of electronic sensors integrated with a microwell array for confining analytes and/or particles for analytical reactions and a method for identifying microwells containing analytes and/or particles by passing a sensor-active reagent over the array and correlating sensor response times to the presence or absence of analytes or particles. Such detection of analyte- or particle-containing microwells may be used as a step in additional noise reduction methods.
公开/授权文献:
IPC结构图谱:
| H | 电学 |
| --H01 | 基本电气元件 |
| ----H01M | 用于直接转变化学能为电能的方法或装置，例如电池组 |
| ------H01M8/00 | 燃料电池；及其制造 |
| --------H01M8/04 | .辅助装置或方法，例如用于压力控制的，用于流体循环的 |