基本信息:
- 专利标题： Methods for controlling pests using RNAi
- 申请号：EP11157036.2 申请日：2007-01-12
- 公开(公告)号：EP2347759A3 公开(公告)日：2011-12-14
- 发明人： van Bleu, Els , Kubler, Laurent , Raemaekers, Romaan , Bogaert, Thierry , Plaetinck, Geert
- 申请人： deVGen N.V.
- 申请人地址： Technologiepark 30 9052 Zwijnaarde BE
- 专利权人： deVGen N.V.
- 当前专利权人： deVGen N.V.
- 当前专利权人地址： Technologiepark 30 9052 Zwijnaarde BE
- 代理机构： De Clercq, Ann G. Y.
- 优先权： US758191P 20060112; US771160P 20060207; US837910P 20060816; US875362P 20061218; EP06447008 20060112
- 主分类号： A61K31/711
- IPC分类号： A61K31/711 ; A61K31/7105 ; C12N5/10 ; A01N57/16 ; A01N61/00
摘要：
The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside the insect cell(s) and whereby the double-stranded RNA is taken up by the intact insect cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from insect pests. Alternatively, the methods are used for treating and/or preventing insect infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable insect target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.
公开/授权文献:
- EP2347759B1 Methods for controlling pests using RNAi 公开/授权日：2017-10-18
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/70 | .碳水化合物；糖；其衍生物 |
| ----------A61K31/7088 | ..含有3个或更多个核苷或核苷酸的化合物 |
| ------------A61K31/711 | ...天然脱氧核糖核酸，即仅含有与腺嘌呤、鸟嘌呤、胞嘧啶、尿嘧啶或胸腺嘧啶相连的2′脱氧核糖并含有3′,5′磷酸二酯键的 |