EP2238242B9 TRANSFERASES AND OXIDOREDUCTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
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基本信息:
- 专利标题： TRANSFERASES AND OXIDOREDUCTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
- 专利标题（中）：转移酶，和氧化还原酶，用于生产和使用的核酸编码AND METHOD
- 申请号：EP08869698.4 申请日：2008-12-31
- 公开(公告)号：EP2238242B9 公开(公告)日：2015-06-10
- 发明人： WEINER, David , LUGINBUHL, Peter , BUENO, Analia , CUENCA, Joslin , MARASCO, Erin
- 申请人： BASF Enzymes LLC
- 申请人地址： 3550 John Hopkins Court San Diego, CA 92121 US
- 专利权人： BASF Enzymes LLC
- 当前专利权人： BASF ENZYMES LLC
- 当前专利权人地址： BASF ENZYMES LLC
- 代理机构： Bühler, Dirk
- 优先权： US18868P 20080103
- 国际公布： WO2009088949 20090716
- 主分类号： C12N9/10
- IPC分类号： C12N9/10 ; C12N9/02 ; C12Q1/48 ; C12Q1/26 ; C07K14/38 ; C07K16/40 ; C07K9/00 ; A61K38/44 ; A61K38/45
摘要：
This invention relates generally to enzymes, polynucleotides encoding the enzymes, the use of such polynucleotides and polypeptides and more specifically to enzymes having transferase activity, e.g., transaminase activity, e.g., d-amino-acid transferase activity, and/or oxidoreductase activity, e.g., dehydrogenase activity, e.g., damino-acid dehydrogenase activity, and/or catalyze the transfer of a chemical group, catalyze transamination, catalyze the reaction: D-alanine + 2-oxoglutarate pyruvate + D-glutamate, and/or catalyze an oxidation-reduction reaction, catalyze the removal of hydrogen atoms, and/or catalyze the reaction: D-amino acid + H 2 O + acceptor a 2-oxo acid + NH 3 + reduced acceptor. Thus, the invention provides enzymes, compositions, methods for production of pharmaceutical compositions, pharmaceutical intermediates, antibiotics, sweeteners, peptide enzymes, peptide hormones, fuel and fuel additive compositions, foods and food additives, beverage and beverage additives, feeds and feed additives, drugs and drug additives, dietary supplements, textiles, wood, paper, pulp, and detergents comprising the polypeptides or polynucleotides in accordance with the invention.