EP2217596B8 BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS MODULATORS OF THE ACTIVITY OF GPR119
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基本信息:
- 专利标题： BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS MODULATORS OF THE ACTIVITY OF GPR119
- 专利标题（中）：双环杂环衍生物及其视为活动GPR 119的调节剂
- 申请号：EP08832779.6 申请日：2008-10-20
- 公开(公告)号：EP2217596B8 公开(公告)日：2013-11-20
- 发明人： XIA, Yan , BOYLE, Craig, D. , GREENLEE, William, J. , CHACKALAMANNIL, Samuel , JAYNE, Charles, Lee , STAMFORD, Andrew, W. , DAI, Xing , HARRIS, Joel, M. , NEUSTADT, Bernard, R. , NEELAMKAVIL, Santhosh, Francis , SHAH, Unmesh, G. , LANKIN, Claire, M. , LIU, Hong
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： MERCK SHARP & DOHME LLC, RAHWAY, US
- 当前专利权人地址： MERCK SHARP & DOHME LLC, RAHWAY, US
- 代理机构： Jaap, David Robert
- 优先权： US981677P 20071022
- 国际公布： WO2009055331 20090430
- 主分类号： C07D451/06
- IPC分类号： C07D451/06 ; C07D471/08 ; C07D498/08 ; C07D487/08 ; C07D491/08 ; A61K31/46 ; A61K31/439 ; A61K31/506 ; A61K31/537 ; A61P3/00 ; C07D401/14 ; C07D495/08
摘要：
The present invention relates to Bicyclic Heterocycle Derivatives, compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D451/00 | 杂环化合物，含有8-氮杂二环 |
| --------C07D451/02 | .含有不进一步稠合的8-氮杂二环 |
| ----------C07D451/04 | ..有杂原子直接连在8-氮杂二环 |
| ------------C07D451/06 | ...氧原子 |