基本信息:
- 专利标题： METHOD FOR PRODUCING NORBORNENE DERIVATIVE
- 专利标题（中）：用于生产降冰片烯衍生物
- 申请号：EP08791783.7 申请日：2008-07-29
- 公开(公告)号：EP2174922A1 公开(公告)日：2010-04-14
- 发明人： KOMATSU, Shinichi , SHOKO, Toshikatsu , KAMINADE, Tadahiro
- 申请人： Nippon Oil Corporation
- 申请人地址： 3-12, Nishi-shimbashi 1-chome Minato-ku Tokyo 105-8412 JP
- 专利权人： Nippon Oil Corporation
- 当前专利权人： Nippon Oil Corporation
- 当前专利权人地址： 3-12, Nishi-shimbashi 1-chome Minato-ku Tokyo 105-8412 JP
- 代理机构： HOFFMANN EITLE
- 优先权： JP2007197295 20070730; JP2008169339 20080627
- 国际公布： WO2009017100 20090205
- 主分类号： C07C2/86
- IPC分类号： C07C2/86 ; C07C13/605 ; C07B61/00
摘要：
A method for producing a norbornene derivative wherein,
in the presence of palladium and at least one selected from phosphorus compounds represented by the following General Formulae (1) and (2):
[in Formula (1), R 1 , R 2 , R 3 and R 4 each independently represent a hydrogen atom or the like, and R 5 and R 6 each independently represent a branched chain saturated hydrocarbon group having 3 to 10 carbon atoms or the like], and
[in Formula (2), R 7 represents a branched chain saturated hydrocarbon group having 3 to 10 carbon atoms],
a norbornadiene derivative represented by the following General Formula (3):
[in Formula (3), R 8 , R 9 , R 10 , R 11 and R 12 each independently represent a hydrogen atom or the like, 1 represents an integer of 0 or 1, m represents an integer of 0 or 1, and n represents an integer of 0 or 1], and a bromine compound represented by the following General Formula (4):
[Chemical Formula 4] Br-Z-R 13 (4)
[in Formula (4), Z represents a phenylene group or the like, and R 13 represents a hydrogen atom or the like] are reacted with each other, to thereby obtain a norbornene derivative represented by the following General Formula(5):
[in Formula (5), R 14 , R 15 , R 16 , R 17 and R 18 each independently represent a hydrogen atom or the like, Z represents a phenylene group or the like, R 19 represents a hydrogen atom or the like, 1 represents an integer of 0 or 1, m represents an integer of 0 or 1, and n represents an integer of 0 or 1], the norbornene derivative having a configuration of a substituent represented by Z in General Formula (5) that is an exo configuration.
in the presence of palladium and at least one selected from phosphorus compounds represented by the following General Formulae (1) and (2):
[in Formula (1), R 1 , R 2 , R 3 and R 4 each independently represent a hydrogen atom or the like, and R 5 and R 6 each independently represent a branched chain saturated hydrocarbon group having 3 to 10 carbon atoms or the like], and
[in Formula (2), R 7 represents a branched chain saturated hydrocarbon group having 3 to 10 carbon atoms],
a norbornadiene derivative represented by the following General Formula (3):
[in Formula (3), R 8 , R 9 , R 10 , R 11 and R 12 each independently represent a hydrogen atom or the like, 1 represents an integer of 0 or 1, m represents an integer of 0 or 1, and n represents an integer of 0 or 1], and a bromine compound represented by the following General Formula (4):
[Chemical Formula 4] Br-Z-R 13 (4)
[in Formula (4), Z represents a phenylene group or the like, and R 13 represents a hydrogen atom or the like] are reacted with each other, to thereby obtain a norbornene derivative represented by the following General Formula(5):
[in Formula (5), R 14 , R 15 , R 16 , R 17 and R 18 each independently represent a hydrogen atom or the like, Z represents a phenylene group or the like, R 19 represents a hydrogen atom or the like, 1 represents an integer of 0 or 1, m represents an integer of 0 or 1, and n represents an integer of 0 or 1], the norbornene derivative having a configuration of a substituent represented by Z in General Formula (5) that is an exo configuration.