基本信息:
- 专利标题： SULFUR COMPOUNDS AS INHIIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE
- 专利标题（中）：硫化合物AS丙型肝炎病毒的NS3丝氨酸蛋白酶抑制剂的
- 申请号：EP08742663.1 申请日：2008-04-08
- 公开(公告)号：EP2134739B1 公开(公告)日：2010-12-01
- 发明人： VELAZQUEZ, Francisco , BOGEN, Stephane, L. , ARASAPPAN, Ashok , VENKATRAMAN, Srikanth , NJOROGE, F., George , SHIH, Neng-Yang
- 申请人： Schering Corporation
- 申请人地址： 2000 Galloping Hill Road Kenilworth, NJ 07033-0530 US
- 专利权人： Schering Corporation
- 当前专利权人： MERCK SHARP & DOHME LLC, RAHWAY, US
- 当前专利权人地址： MERCK SHARP & DOHME LLC, RAHWAY, US
- 代理机构： van den Broek, Ludovicus A.G.M.
- 优先权： US733479 20070410
- 国际公布： WO2008124148 20081016
- 主分类号： C07K5/08
- IPC分类号： C07K5/08
摘要：
The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.