基本信息:
- 专利标题： NOVEL BENZOXATHIIN DERIVATIVE
- 专利标题（中）：新的苯并吖庚因衍生物
- 申请号：EP06822742.0 申请日：2006-10-25
- 公开(公告)号：EP1944301A1 公开(公告)日：2008-07-16
- 发明人： SASAKI, Takahide , SATO, Nagaaki , TAKAHASHI, Toshiyuki , MIZUTANI, Takashi
- 申请人： BANYU PHARMACEUTICAL CO., LTD.
- 申请人地址： Kitanomaru Square 1-13-12, Kudan-kita Chiyoda-ku Tokyo 102-8667 JP
- 专利权人： BANYU PHARMACEUTICAL CO., LTD.
- 当前专利权人： BANYU PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： Kitanomaru Square 1-13-12, Kudan-kita Chiyoda-ku Tokyo 102-8667 JP
- 代理机构： Buchan, Gavin MacNicol
- 优先权： JP2005312956 20051027
- 国际公布： WO2007049798 20070503
- 主分类号： C07D327/06
- IPC分类号： C07D327/06 ; A61K31/4025 ; A61K31/4365 ; A61K31/4535 ; A61K31/454 ; A61P1/16 ; A61P3/04 ; A61P3/06 ; A61P3/10 ; A61P5/00 ; A61P9/04 ; A61P9/10 ; A61P9/12 ; A61P13/12 ; A61P19/06 ; A61P25/00 ; A61P25/08 ; A61P25/16 ; A61P25/20 ; A61P25/22
摘要：
Disclosed is a compound represented by the formula (I) below and a pharmaceutically acceptable salt thereof.
This compound is useful for treatment of obesity, diabetes and the like. [In the formula (I), Ar represents a benzene ring or the like; X 1 represents a nitrogen atom, a sulfur atom or the like; R1 represents an aryl group or the like; X 2 represents a group represented by the following formula (II): (wherein R 4 and R 5 respectively represent a lower alkyl group or the like, and m represents a number of 2-4) or the like; one of X and Y represents an oxygen atom and the other represents a sulfanyl group or the like; and X 3 -X 6 respectively represent -CH-, a nitrogen atom or the like.
摘要（中）：
This compound is useful for treatment of obesity, diabetes and the like. [In the formula (I), Ar represents a benzene ring or the like; X 1 represents a nitrogen atom, a sulfur atom or the like; R1 represents an aryl group or the like; X 2 represents a group represented by the following formula (II): (wherein R 4 and R 5 respectively represent a lower alkyl group or the like, and m represents a number of 2-4) or the like; one of X and Y represents an oxygen atom and the other represents a sulfanyl group or the like; and X 3 -X 6 respectively represent -CH-, a nitrogen atom or the like.
公开了由下式（I）表示的化合物及其药学上可接受的盐。 该化合物可用于治疗肥胖症，糖尿病等。 [式（I）中，Ar表示苯环等; X1代表氮原子，硫原子等; R1代表芳基等; X2表示由下式（II）表示的基团：（其中R4和R5分别表示低级烷基等，m表示2-4的数）等等; X和Y中的一个代表氧原子，另一个代表硫烷基等; 和X 3 -X 6分别代表-CH-，氮原子等。
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D327/00 | 杂环化合物，含有氧原子和硫原子作为仅有的杂环原子的环 |
| --------C07D327/02 | .1个氧原子和1个硫原子 |
| ----------C07D327/06 | ..六元环 |