发明公开
EP1846000A4 PHARMACEUTICAL COMPOSITIONS CONTAINING BISPHOSPHONATE FOR IMPROVING ORAL ABSORPTION
审中-公开
基本信息:
- 专利标题： PHARMACEUTICAL COMPOSITIONS CONTAINING BISPHOSPHONATE FOR IMPROVING ORAL ABSORPTION
- 专利标题（中）：药物组合物的双膦酸盐，以提高口服吸收
- 申请号：EP06701990 申请日：2006-01-03
- 公开(公告)号：EP1846000A4 公开(公告)日：2008-07-30
- 发明人： SHIN HEE-JONG , KI MIN-HYO , CHOI MEE-HWA , LEE JIN-WOO
- 申请人： CHONG KUN DANG PHARM CORP
- 专利权人： CHONG KUN DANG PHARM CORP
- 当前专利权人： CHONG KUN DANG PHARM CORP
- 优先权： KR20050008711 2005-01-31
- 主分类号： A61K31/663
- IPC分类号： A61K31/663 ; A61K9/20 ; A61K9/48 ; A61K47/36 ; A61P19/10
摘要：
Provided is a pharmaceutical composition having improved oral absorption of a bisphosphonate drug, comprising at least one active substance selected from bisphosphonate drugs having non-permeability to a lipid biomembrane due to ionization and high water-solubility in vivo and having bioavailability of less than 10%, and at least one selected from biocompatible water-soluble chitosan, as essential ingredients.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/66 | .磷的化合物 |
| ----------A61K31/661 | ..不具有P—C键的磷酸或其酯，例如磷酸二氢水杨酸酯、双金霉素、马拉硫磷 |
| ------------A61K31/663 | ...具有两个或多个磷酸基团或其酯的化合物，例如氯屈膦酸、帕米膦酸 |