EP1660144B1 IMPLANTABLE OR INSERTABLE MEDICAL DEVICES CONTAINING GRAFT COPOLYMER FOR CONTROLLED DELIVERY OF THERAPEUTIC AGENTS
有权
基本信息:
- 专利标题： IMPLANTABLE OR INSERTABLE MEDICAL DEVICES CONTAINING GRAFT COPOLYMER FOR CONTROLLED DELIVERY OF THERAPEUTIC AGENTS
- 专利标题（中）：与接枝共聚物用于治疗药物的控制下交付植入或可插入医疗器械
- 申请号：EP04779545.5 申请日：2004-07-29
- 公开(公告)号：EP1660144B1 公开(公告)日：2010-11-10
- 发明人： RICHARD, Robert, E. , STRICKLER, Frederick, H.
- 申请人： Boston Scientific Limited
- 申请人地址： P.O. Box 1317 Seaston House Hastings Christ Church BB
- 专利权人： Boston Scientific Limited
- 当前专利权人： Boston Scientific Limited
- 当前专利权人地址： P.O. Box 1317 Seaston House Hastings Christ Church BB
- 代理机构： Vossius & Partner
- 优先权： US632413 20030731
- 国际公布： WO2005011766 20050210
- 主分类号： A61L27/26
- IPC分类号： A61L27/26 ; A61L27/34 ; A61L29/04 ; A61L29/08 ; A61L31/04 ; A61L31/10
摘要：
Implantable or insertable medical devices are described. The medical devices comprise (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymer release region comprises a graft copolymer, which further comprises a main chain and a plurality of side chains. One of (a) the main chain and (b) the side chains corresponds to a rubbery phase within the release region at ambient temperatures, while the other corresponds to a hard phase within the release layer at ambient temperatures. Typically, the graft copolymer will comprise one glass transition temperature below ambient temperature and another second glass transition temperature above ambient temperature. Also described are methods for forming the above graft copolymers, methods for administering a therapeutic agent to a patient using the above implantable or insertable medical devices, as well as methods for making the above devices.
公开/授权文献:
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61L | 材料或物体消毒的一般方法或装置；空气的灭菌、消毒或除臭；绷带、敷料、吸收垫或外科用品的化学方面；绷带、敷料、吸收垫或外科用品的材料 |
| ------A61L27/00 | 假体材料或假体被覆材料 |
| --------A61L27/02 | .无机材料 |
| ----------A61L27/26 | ..大分子物质的混合物 |